Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development (Q22241837)

7 February 2023

A. A. Nierenberg

1

Andrew A

Nierenberg

1 reference

7 February 2023

C. Kansky

2

Christine

Kansky

1 reference

7 February 2023

B. P. Brennan

3

Brian P

Brennan

1 reference

7 February 2023

R. C. Shelton

4

Richard C

Shelton

1 reference

7 February 2023

D. V. Iosifescu

6

Dan V

Iosifescu

1 reference

Australian and New Zealand Journal of Psychiatry

7 February 2023

language of work or name

English

0 references

publication date

18 June 2012

0 references

published in

0 references

volume

47

0 references

issue

1

0 references

page(s)

26-42

0 references

cites work

Melatonin and nitric oxide: two required antagonists for mitochondrial homeostasis

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin role in the mitochondrial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin, mitochondria, and cellular bioenergetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues of chick and their inhibition by light

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Delaying the mitochondrial decay of aging with acetylcarnitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Aging brain: effect of acetyl-L-carnitine treatment on rat brain energy and phospholipid metabolism. A study by 31P and 1H NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Defective brain energy metabolism shown by in vivo 31P MR spectroscopy in 28 patients with mitochondrial cytopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin add-on in manic patients with treatment resistant insomnia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Folate, Vitamin B12, and Neuropsychiatric Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Homocysteine, folate, methylation, and monoamine metabolism in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Negative effects of melatonin on depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The switch mechanism and the bipolar/unipolar dichotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Abnormalities in mitochondrial structure in cells from patients with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

p53 in neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Brain metabolic alterations in medication-free patients with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Phosphorus magnetic resonance spectroscopy of patients with mitochondrial cytopathies demonstrates decreased levels of brain phosphocreatine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

21 January 2018

ATP and brain function

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Assessment of coenzyme Q10 tolerability in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Burning mouth syndrome (BMS): double blind controlled study of alpha-lipoic acid (thioctic acid) therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Pharmacological Treatment Patterns at Study Entry for the First 500 STEP-BD Participants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

A randomized sequential trial of creatine in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Clinical experience with thioctacid (thioctic acid) in the treatment of distal symmetric polyneuropathy in Korean diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Reduced intracellular pH in the basal ganglia and whole brain measured by 31P-MRS in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Safety assessment of coenzyme Q10 (CoQ10).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The role of carnitine in normal and altered fatty acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Residual symptom recovery from major affective episodes in bipolar disorders and rapid episode relapse/recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Allostatic load in bipolar disorder: implications for pathophysiology and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Role of mitochondrial DNA in calcium signaling abnormality in bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial DNA-dependent effects of valproate on mitochondrial calcium levels in transmitochondrial cybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Molecular evidence for mitochondrial dysfunction in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Direct antioxidant properties of creatine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin mitigates mitochondrial malfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin and mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effect of controlled-release melatonin on sleep quality, mood, and quality of life in subjects with seasonal or weather-associated changes in mood and behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin treatment of winter depression: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Open trial of S-adenosylmethionine for treatment of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Multinuclear magnetic resonance spectroscopy of high-energy phosphate metabolites in human brain following oral supplementation of creatine-monohydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Acetyl-L-carnitine treatment in minimal hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Treatment of alcohol-related liver disease with thioctic acid: a six month randomised double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Novel drugs and therapeutic targets for severe mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Ethanolamine and phosphoethanolamine inhibit mitochondrial function in vitro: implications for mitochondrial dysfunction hypothesis in depression and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Choline, myo-inositol and mood in bipolar disorder: a proton magnetic resonance spectroscopic imaging study of the anterior cingulate cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Brain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: family-based association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Sequence and functional analyses of mtDNA in a maternally inherited family with bipolar disorder and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial DNA 3644T-->C mutation associated with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effect of antioxidant diets on mitochondrial gene expression in rat brain during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Alpha-lipoic acid as a biological antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Inhibition of Alzheimer beta-fibrillogenesis by melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Synthesis of N-acetyl-l-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The selfish brain: competition for energy resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

31P-MRS study of acetyl-L-carnitine treatment in geriatric depression: preliminary results

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Energy requirements for two aspects of phospholipid metabolism in mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrially mediated plasticity in the pathophysiology and treatment of bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Regulation of antioxidant enzymes: a significant role for melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine monohydrate in resistant depression: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Adjunctive nutraceuticals with standard pharmacotherapies in bipolar disorder: a systematic review of clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The effect of mood stabilizer lithium on expression and activity of glutathione s-transferase isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial involvement in psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Clinical trials of coenzyme Q10 in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Whole-genome association study of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Long-term acetyl-L-carnitine treatment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Q10 therapy in patients with idiopathic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The mitochondrial cocktail: rationale for combined nutraceutical therapy in mitochondrial cytopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Mitochondrial DNA mutations in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

American College of Sports Medicine roundtable. The physiological and health effects of oral creatine supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of alpha-lipoic acid supplementation in peripheral arterial disease: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Defects of mitochondrial electron transport chain in bipolar disorder: implications for mood-stabilizing treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

The role of mitochondrial porins and the permeability transition pore in learning and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Cross-national epidemiology of major depression and bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Melatonin attenuates diabetes-induced oxidative stress in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Lipoic acid in multiple sclerosis: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Ca2+ influx–independent synaptic potentiation mediated by mitochondrial Na+-Ca2+ exchanger and protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

31P Nuclear magnetic resonance spectroscopy findings in bipolar illness: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

A double-blind, randomised, controlled clinical trial of acetyl-L-carnitine vs. amisulpride in the treatment of dysthymia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Double-Blind, Crossover, Placebo-Controlled Clinical Trial with L-Acetylcarnitine in Patients with Degenerative Cerebellar Ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

Dietary supplement creatine protects against traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

The mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Melatonin: detoxification of oxygen and nitrogen-based toxic reactants.

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Mitochondrial regulation by melatonin and its metabolites.

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis.

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant alpha-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study)

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Effects of l-Acetylcarnitine on Cirrhotic Patients with Hepatic Coma: Randomized Double-Blind, Placebo-Controlled Trial

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

CNS energy metabolism as related to function

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Oral creatine supplementation and athletic performance: a critical review

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Observed effects of creatine monohydrate in a patient with depression and fibromyalgia

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in human immunodeficiency virus-associated cognitive impairment. Dana Consortium on the Therapy of HIV Dementia and Related Cognitive Disorders

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Acetyl-L-carnitine and α-lipoic acid: possible neurotherapeutic agents for mood disorders?

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Melatonin: an established antioxidant worthy of use in clinical trials.

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Effects of exogenous melatonin administration and withdrawal in five patients with rapid-cycling bipolar disorder

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Open study of creatine monohydrate in treatment-resistant posttraumatic stress disorder.

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Lack of efficacy of 5 grams daily of creatine in schizophrenia: a randomized, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1177%2F0004867412449303

7 January 2021

Identifiers

DOI

10.1177/0004867412449303

0 references