Crohn's disease: an immune deficiency state (Q22252579)

Europe PubMed Central

title

Crohn's disease: an immune deficiency state (English)

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Anthony W Segal

4

Anthony W.

Segal

1 reference

7 February 2023

Daniel J B Marks

1

Daniel J. B.

Marks

1 reference

7 February 2023

Farooq Z Rahman

series ordinal

2

author given names

Farooq Z.

author last names

Rahman

1 reference

7 February 2023

Gavin W Sewell

series ordinal

3

author given names

Gavin W.

author last names

Sewell

1 reference

Clinical Reviews in Allergy & Immunology

7 February 2023

language of work or name

English

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publication date

February 2010

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published in

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volume

38

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issue

1

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page(s)

20-31

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exact match

https://scigraph.springernature.com/pub.10.1007/s12016-009-8133-2

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cites work

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

19 March 2017

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Trichuris suis therapy in Crohn's disease

19 March 2017

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

19 March 2017

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Killing activity of neutrophils is mediated through activation of proteases by K+ flux

19 March 2017

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

19 March 2017

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

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Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55

19 March 2017

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Thickness of adherent mucus gel on colonic mucosa in humans and its relevance to colitis

19 March 2017

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Inflammatory Bowel Disease

19 March 2017

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

19 March 2017

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Interleukin-23R Arg381Gln is associated with susceptibility to Crohn's disease but not with phenotype in an Italian population

19 March 2017

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Two-year combination antibiotic therapy with clarithromycin, rifabutin, and clofazimine for Crohn's disease

19 March 2017

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Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

19 March 2017

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Functional variants of OCTN cation transporter genes are associated with Crohn disease

19 March 2017

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

19 March 2017

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Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

19 March 2017

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Mapping of a susceptibility locus for Crohn's disease on chromosome 16

19 March 2017

1 reference

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Personal genomes: The case of the missing heritability

19 March 2017

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Human IRGM induces autophagy to eliminate intracellular mycobacteria

7 April 2017

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Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

7 April 2017

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The Interleukin-23 / Interleukin-17 axis in intestinal inflammation.

27 September 2017

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Phagocyte dysfunction and inflammatory bowel disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Gastrointestinal microbiology enters the metagenomics era.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Impaired neutrophil chemotaxis in Crohn's disease relates to reduced production of chemokines and can be augmented by granulocyte-colony stimulating factor.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Can unresolved infection precipitate autoimmune disease?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Defective acute inflammation in Crohn's disease: a clinical investigation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Phagocytosis: elegant complexity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Inflammatory resolution: new opportunities for drug discovery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Bugs and the gut: an unstable marriage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Crohn's disease: the cold chain hypothesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Infliximab treatment of rheumatoid arthritis and Crohn's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Crohn's disease and the NOD2 gene: a role for paneth cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Hygiene hypothesis: fact or fiction?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

The immunology of mucosal models of inflammation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Mucin gene expression in intestinal epithelial cells in Crohn's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Does the failure to acquire helminthic parasites predispose to Crohn's disease?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

A clinicopathological classification of granulomatous disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Lack of support for a common etiology in Johne's disease of animals and Crohn's disease in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Urinary complications of Crohn's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Elemental diet as primary treatment of acute Crohn's disease: a controlled trial

27 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

27 September 2017

12 December 2020

Role of the faecal stream in the maintenance of Crohn's colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Neutrophil dysfunction in Crohn's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Intestinal permeability of 51Cr-labelled ethylenediaminetetraacetic acid in patients with Crohn's disease and their healthy relatives

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

An exuberant inflammatory response to E coli: implications for the pathogenesis of ulcerative colitis and pyoderma gangrenosum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Antagonist. Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

The influence of cigarette smoking on cytokine levels in patients with inflammatory bowel disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Infectious gastroenteritis and risk of developing inflammatory bowel disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Development of Crohn's disease in a patient with multiple sclerosis treated with copaxone

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Mortality by medication use among patients with inflammatory bowel disease, 1996-2003.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Improvement of real-time polymerase chain reaction for quantifying TNF-alpha mRNA expression in inflamed colorectal mucosa: an approach to optimize procedures for clinical use.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Development of Crohn's disease in a patient taking etanercept.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn?s disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Effects of cigarette smoke on the immune system

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Possible role of mycobacteria in inflammatory bowel disease. I. An unclassified Mycobacterium species isolated from patients with Crohn's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568313

Analysis of results of surgical treatment in Crohn's disease

29 November 2018

1 reference

12 December 2020

Chronic granulomatous disease

1 reference

12 December 2020

A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease

1 reference

12 December 2020

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

1 reference

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

12 December 2020

Serum inhibitors of leukocyte chemotaxis in Crohn's disease and ulcerative colitis

1 reference

12 December 2020

1 reference

12 December 2020

Granulomatous enterocolitis associated with Hermansky-Pudlak syndrome

1 reference

12 December 2020

Quantitative PCR analysis of TNF-alpha and IL-1 beta mRNA levels in pediatric IBD mucosal biopsies

1 reference

12 December 2020

Study of the carbohydrate content of mucus glycoproteins from normal and diseased colons

1 reference

12 December 2020

Granulomas of the gut in Crohn's disease. A step sectioning study

1 reference

12 December 2020

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

1 reference

12 December 2020

A freeze fracture study of Crohn's disease of the terminal ileum: changes in epithelial tight junction organization

1 reference

12 December 2020

Chediak-Higashi syndrome with intestinal complication. Report of a case

1 reference

12 December 2020

Delayed perineal wound healing after proctectomy for Crohn's colitis

1 reference

12 December 2020

Audit of sepsis in operations for inflammatory bowel disease

1 reference

12 December 2020

Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

1 reference

12 December 2020

1 reference

12 December 2020

10.1007/S12016-009-8133-2

Identifiers

DOI

1 reference

2804383

0 references

2804383

1 reference

1 reference

1 reference