Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts (Q22253167)

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English	Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts	scientific article

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Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts (English)

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Adrenoceptor alpha 1A

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GOA release 2020-03-11

intracellular signal transduction

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GOA release 2020-03-11

author name string

L M Ballou

1

author given names

L M

author last names

Ballou

1 reference

8 February 2023

M E Cross

2

author given names

M E

author last names

Cross

1 reference

8 February 2023

S Huang

3

author given names

S

author last names

Huang

1 reference

8 February 2023

E M McReynolds

4

author given names

E M

author last names

McReynolds

1 reference

8 February 2023

B X Zhang

5

author given names

B X

author last names

Zhang

1 reference

8 February 2023

R Z Lin

6

author given names

R Z

author last names

Lin

1 reference

8 February 2023

language of work or name

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publication date

18 February 2000

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Journal of Biological Chemistry

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275

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4803-9

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7

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

The modular phosphorylation and activation of p70s6k.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Dual requirement for a newly identified phosphorylation site in p70s6k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Phosphorylation of the cAMP response element-binding protein and activation of transcription by alpha1 adrenergic receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Gq signaling in cardiac adaptation and maladaptation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

1 reference

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21 January 2018

Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

21 January 2018

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

7 January 2021

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Mechanism of activation of protein kinase B by insulin and IGF-1

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7 January 2021

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Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

1 reference

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7 January 2021

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An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells

1 reference

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7 January 2021

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G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

1 reference

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7 January 2021

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Enhancement by adenosine of insulin-induced activation of phosphoinositide 3-kinase and protein kinase B in rat adipocytes

1 reference

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7 January 2021

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alpha(1A) adrenergic receptor induces eukaryotic initiation factor 4E-binding protein 1 phosphorylation via a Ca(2+)-dependent pathway independent of phosphatidylinositol 3-kinase/Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.7.4803

7 January 2021

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Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

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7 January 2021

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Activation of purinergic receptors triggers oscillatory contractions in adult rat ventricular myocytes

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Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 S6 kinase

1 reference

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7 January 2021

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