Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit (Q24291434)

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9 November 2019

title

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit (English)

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9 November 2019

0 references

1 reference

GOA release 2020-03-11

telomere maintenance

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Nijmegen breakage syndrome

GOA release 2020-03-11

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4

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9 November 2019

Ian M Ahearn

8

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9 November 2019

author name string

V Ranganathan

1

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9 November 2019

W F Heine

2

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9 November 2019

D N Ciccone

3

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9 November 2019

X Wu

5

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9 November 2019

S Chang

6

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9 November 2019

H Hai

7

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9 November 2019

D M Livingston

9

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9 November 2019

I Resnick

10

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9 November 2019

F Rosen

11

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9 November 2019

E Seemanova

12

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9 November 2019

P Jarolim

13

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9 November 2019

R A DePinho

14

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D T Weaver

15

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9 November 2019

language of work or name

English

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publication date

1 June 2001

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9 November 2019

number of pages

5

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inferred from page(s)

published in

Current Biology

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9 November 2019

volume

11

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9 November 2019

issue

12

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9 November 2019

page(s)

962-966

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A new chromosomal instability disorder: the Nijmegen breakage syndrome

9 November 2019

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Familial microcephaly with normal intelligence, immunodeficiency, and risk for lymphoreticular malignancies: a new autosomal recessive disorder

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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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The many interfaces of Mre11

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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

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NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

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7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

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Telomeres shorten during ageing of human fibroblasts

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Influence of ATM function on telomere metabolism

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Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

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Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

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7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

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Independence of R/M/N focus formation and the presence of intact BRCA1.

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Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

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7 January 2021

Telomere length predicts replicative capacity of human fibroblasts

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7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

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7 January 2021

Telomeres: moonlighting by DNA repair proteins

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DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

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7 January 2021

Ku is associated with the telomere in mammals

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Control of telomere length by the human telomeric protein TRF1

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7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

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7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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7 January 2021

Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae

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Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

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7 January 2021

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene

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7 January 2021

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

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7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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Identifiers

DOI

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9 November 2019

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