Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4 (Q24292312)

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English	Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4	scientific article

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scholarly article

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Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4 (English)

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Potassium voltage-gated channel interacting protein 4

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GOA release 2020-03-11

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8

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author name string

Yuichi Morohashi

1

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Noriyuki Hatano

2

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Susumu Ohya

3

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Rie Takikawa

4

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Tomonari Watabiki

5

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Nobumasa Takasugi

6

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Yuji Imaizumi

7

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Takeshi Iwatsubo

9

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language of work or name

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publication date

26 April 2002

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Journal of Biological Chemistry

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277

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17

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14965-75

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Endoproteolytic processing and stabilization of wild-type and mutant presenilin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

A common enzyme connects notch signaling and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Calsenilin reverses presenilin-mediated enhancement of calcium signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Modulation of A-type potassium channels by a family of calcium sensors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Molecular cloning and tissue distribution of an alternatively spliced variant of an A-type K+ channel alpha-subunit, Kv4.3 in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Molecular cloning and expression of the novel splice variants of K(+) channel-interacting protein 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the Abeta 42-promoting effects of Alzheimer mutant presenilin 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Promoter characterization of the rat gene for Ca2+-binding protein regucalcin. Transcriptional regulation by signaling factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Apoptosis in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Primary cultures of neuronal and non-neuronal rat brain cells secrete similar proportions of amyloid β peptides ending at Aβ40 and Aβ42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

21 January 2018

Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Presenilin-mediated modulation of capacitative calcium entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of calcium binding proteins by 45Ca autoradiography on nitrocellulose membrane after sodium dodecyl sulfate gel electrophoresis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Characteristics of transient outward currents in single smooth muscle cells from the ureter of the guinea-pig

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetic modulation of Kv4-mediated A-current by arachidonic acid is dependent on potassium channel interacting proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200897200

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1074/JBC.M200897200

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