JNK1 phosphorylates SIRT1 and promotes its enzymatic activity (Q24293117)

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

Mitogen-activated protein kinase 8

1 reference

GOA release 2020-03-11

histone H3 deacetylation

1 reference

GOA release 2020-03-11

Rafael de Cabo

6

0 references

author name string

Nargis Nasrin

1

0 references

Virendar K Kaushik

2

0 references

Eric Fortier

3

0 references

Daniel Wall

4

0 references

Kevin J Pearson

5

0 references

Laura Bordone

Creative Commons CC0 License

7

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language of work or name

English

0 references

publication date

2009

0 references

published in

PLOS One

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volume

4

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issue

12

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page(s)

e8414

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copyright license

start time

22 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

The functional contrariety of JNK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

19 March 2017

1 reference

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Negative control of p53 by Sir2alpha promotes cell survival under stress

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

19 March 2017

1 reference

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Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

19 March 2017

1 reference

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The Sir2 family of protein deacetylases

19 March 2017

1 reference

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Genetic pathways that regulate ageing in model organisms

19 March 2017

1 reference

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Sirtuins in mammals: insights into their biological function

19 March 2017

1 reference

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Phosphorylation regulates SIRT1 function.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

JNK2-dependent regulation of SIRT1 protein stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

27 September 2017

1 reference

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MAP kinases and the control of nuclear events

27 September 2017

1 reference

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High levels of oxidative stress globally inhibit gene transcription and histone acetylation

27 September 2017

1 reference

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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

27 September 2017

1 reference

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JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

27 September 2017

1 reference

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Redox signaling and the MAP kinase pathways

27 September 2017

1 reference

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How does calorie restriction work?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

The JNK signal transduction pathway

27 September 2017

1 reference

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Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2793009

Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20027304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20027304

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0008414

1 reference

4341768

ADS bibcode

2009PLoSO...4.8414N

0 references

4341768

1 reference

1 reference

1 reference