Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein (Q24296418)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0035615

AP-2 adaptor complex binding

GOA release 2020-03-11

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0035612

Low density lipoprotein receptor adaptor protein 1

1 reference

GOA release 2020-03-11

Linton M Traub

6

Linton M

Traub

1 reference

30 October 2023

3

Melissa A Edeling

Melissa A

Edeling

1 reference

30 October 2023

2

Peter A Keyel

Peter A

Keyel

1 reference

30 October 2023

Sanjay K Mishra

1

Sanjay K

Mishra

1 reference

30 October 2023

Amie L Dupin

series ordinal

4

author given names

Amie L

author last names

Dupin

1 reference

30 October 2023

David J Owen

series ordinal

5

author given names

David J

author last names

Owen

1 reference

Journal of Biological Chemistry

30 October 2023

language of work or name

English

0 references

publication date

13 May 2005

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published in

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volume

280

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issue

19

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page(s)

19270-80

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cites work

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Three ways to make a vesicle

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Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

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Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

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Molecular architecture and functional model of the endocytic AP2 complex

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Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

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Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection

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Cargo recognition during clathrin-mediated endocytosis: a team effort

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The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors

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The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites

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Distinct saturable pathways for the endocytosis of different tyrosine motifs

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Clathrin-mediated endocytosis in AP-2-depleted cells

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The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor

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Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

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Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor

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ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2

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The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery

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Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis

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Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

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Molecular mechanisms of autosomal recessive hypercholesterolemia.

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Genetics, clinical phenotype, and molecular cell biology of autosomal recessive hypercholesterolemia

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Interaction of two structurally distinct sequence types with the clathrin terminal domain beta-propeller.

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beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin

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Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis

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Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking

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The structure and function of the beta 2-adaptin appendage domain

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Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

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A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain

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Accessory protein recruitment motifs in clathrin-mediated endocytosis

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Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif

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Molecular and Functional Characterization of Clathrin- and AP-2-binding Determinants within a Disordered Domain of Auxilin

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Structural basis for binding of accessory proteins by the appendage domain of GGAs

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EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking

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The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites

21 January 2018

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Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller

21 January 2018

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A novel AP-2 adaptor interaction motif initially identified in the long-splice isoform of synaptojanin 1, SJ170

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M501029200

0 references

Fatcat ID

release_lnfnsjfjhva2dn3zq42yx7tt7m

0 references