Ubiquitin is phosphorylated by PINK1 to activate parkin (Q24296532)

PTEN induced putative kinase 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Yasushi Tamura

4

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Edward A. Fon

12

object named as

Edward A Fon

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Jean-François Trempe

13

object named as

Jean-François Trempe

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author name string

Fumika Koyano

1

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Kei Okatsu

2

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Hidetaka Kosako

3

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Etsu Go

5

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Mayumi Kimura

6

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Yoko Kimura

7

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Hikaru Tsuchiya

8

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Hidehito Yoshihara

9

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Takatsugu Hirokawa

10

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Toshiya Endo

11

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Yasushi Saeki

14

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Keiji Tanaka

15

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Noriyuki Matsuda

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

16

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language of work or name

English

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publication date

5 June 2014

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published in

Nature

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volume

510

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page(s)

162-6

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issue

7503

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cites work

1 reference

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

20 April 2017

1 reference

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

20 April 2017

1 reference

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

20 April 2017

1 reference

Autoregulation of Parkin activity through its ubiquitin-like domain

20 April 2017

1 reference

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

20 April 2017

1 reference

Structure of parkin reveals mechanisms for ubiquitin ligase activation

20 April 2017

1 reference

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

20 April 2017

1 reference

Structure of the human Parkin ligase domain in an autoinhibited state

20 April 2017

1 reference

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease

20 April 2017

1 reference

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Phosphate-binding tag, a new tool to visualize phosphorylated proteins

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

What genetics tells us about the causes and mechanisms of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

Complex I: inhibitors, inhibition and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13392

21 January 2018

Identifiers

DOI

10.1038/NATURE13392

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

5691

1043794606

0 references

5691

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference