Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1 (Q24296806)

iron ion transmembrane transport

GOA release 2020-03-11

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GOA release 2020-03-11

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8

Markus Paulmichl

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Guenter Weiss

object named as

Guenter Weiss

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Matthias Hentze

object named as

Matthias W Hentze

9

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Martina U Muckenthaler

3

object named as

Martina U Muckenthaler

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author name string

Susanne Ludwiczek

1

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Igor Theurl

2

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Martin Jakab

4

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Sabine M Mair

5

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Milan Theurl

6

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Judit Kiss

7

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Markus Paulmichl

8

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Markus Ritter

Altered dietary iron intake is a strong modulator of renal DMT1 expression

10

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language of work or name

English

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publication date

April 2007

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published in

Nature Medicine

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volume

13

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issue

4

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page(s)

448-54

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cites work

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HFE and non-HFE hemochromatosis

21 January 2018

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Mechanisms of iron accumulation in hereditary hemochromatosis

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Hereditary hemochromatosis--a new look at an old disease

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

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Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

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Secondary iron overload

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Pathophysiology of iron overload.

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Mechanisms and regulation of intestinal iron absorption

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The orchestration of body iron intake: how and where do enterocytes receive their cues?

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Balancing acts: molecular control of mammalian iron metabolism

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Mechanisms of cellular iron acquisition: another iron in the fire

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An iron-regulated ferric reductase associated with the absorption of dietary iron

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

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7 January 2021

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

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7 January 2021

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

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7 January 2021

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

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7 January 2021

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

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7 January 2021

The iron transporter DMT1.

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7 January 2021

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

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7 January 2021

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

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7 January 2021

A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway

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Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

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7 January 2021

Hepcidin--a regulator of intestinal iron absorption and iron recycling by macrophages

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7 January 2021

Relationships and distinctions in iron-regulatory networks responding to interrelated signals

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7 January 2021

Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes

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7 January 2021

Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2).

1 reference

7 January 2021

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

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7 January 2021

Additive stimulatory effect of extracellular calcium and potassium on non-transferrin ferric iron uptake by HeLa and K562 cells.

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7 January 2021

Molecular determinants of drug binding and action on L-type calcium channels

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Pharmacology, structure and function of cardiac L-type Ca(2+) channels

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HFE gene knockout produces mouse model of hereditary hemochromatosis

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7 January 2021

Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism

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7 January 2021

Microcytic anemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1 (SCL11A2).

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7 January 2021

Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload

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7 January 2021

Two new human DMT1 gene mutations in a patient with microcytic anemia, low ferritinemia, and liver iron overload.

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7 January 2021

Cellular localization of divalent metal transporter DMT-1 in rat kidney

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7 January 2021

Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice

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7 January 2021

Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes

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7 January 2021

Photodegraded nifedipine stimulates uptake and retention of iron in human epidermal keratinocytes

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Iron and transition metal transport into erythrocytes mediated by nifedipine degradation products and related compounds

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7 January 2021

Divalent metal transporter 1.

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7 January 2021

Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability

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7 January 2021

Cytokine-mediated regulation of iron transport in human monocytic cells

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7 January 2021

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1542

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3454026

1012078575

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Fatcat ID

release_nicqashtpndsjlifcslcj4lofa

0 references

3454026

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference