The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop (Q24297633)

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8 January 2020

title

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop (English)

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8 January 2020

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GOA release 2020-03-11

identical protein binding

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GOA release 2020-03-11

author

Thuy-Ai Nguyen

3

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Moshe Oren

5

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8 January 2020

author name string

Xiongbin Lu

1

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8 January 2020

Ou Ma

2

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8 January 2020

Stephen N Jones

4

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8 January 2020

Lawrence A Donehower

6

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8 January 2020

language of work or name

English

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publication date

1 October 2007

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8 January 2020

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8 January 2020

volume

12

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issue

4

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8 January 2020

page(s)

342-354

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Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The structure and expression of the murine wildtype p53-induced phosphatase 1 (Wip1) gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The p53-Mdm2 module and the ubiquitin system.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Cyclin G recruits PP2A to dephosphorylate Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

A dynamic role of HAUSP in the p53-Mdm2 pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Post-translational modification of p53 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The complexity of p53 stabilization and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The p53 pathway: positive and negative feedback loops

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Cell cycle regulation and p53 activation by protein phosphatase 2C alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Exploiting the p53 pathway for the diagnosis and therapy of human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Phosphorylation of serine 18 regulates distinct p53 functions in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

MDM2 is a central node in the p53 pathway: 12 years and counting

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.08.033

7 January 2021

10.1016/J.CCR.2007.08.033

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

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8 January 2020

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017