The p53 pathway: positive and negative feedback loops (Q29617535)

Europe PubMed Central

title

The p53 pathway: positive and negative feedback loops (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

30 April 2017

author name string

Harris SL

series ordinal

1

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30 April 2017

Levine AJ

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

18 April 2005

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

30 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

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volume

24

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

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page(s)

2899-908

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issue

17

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

p14ARF links the tumour suppressors RB and p53.

30 April 2017

cites work

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7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

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7 January 2021

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

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7 January 2021

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

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7 January 2021

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

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7 January 2021

Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function

1 reference

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7 January 2021

The ubiquitin ligase COP1 is a critical negative regulator of p53

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7 January 2021

p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors

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7 January 2021

Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter

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7 January 2021

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

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7 January 2021

The role of p53 in determining sensitivity to radiotherapy

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7 January 2021

The p53MH algorithm and its application in detecting p53-responsive genes

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7 January 2021

DNA damage checkpoint control in cells exposed to ionizing radiation

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7 January 2021

Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

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7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

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7 January 2021

p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

1 reference

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7 January 2021

Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery.

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7 January 2021

Targeting the p53-MDM2 interaction to treat cancer

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7 January 2021

Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53.

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7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

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7 January 2021

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

1 reference

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7 January 2021

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Regulation of HDM2 activity by the ribosomal protein L11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes

1 reference

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7 January 2021

The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation

1 reference

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7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

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7 January 2021

The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability

1 reference

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7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

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7 January 2021

Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Cyclin a-CDK phosphorylation regulates MDM2 protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

MDM2 and Promyelocytic Leukemia Antagonize Each Other through Their Direct Interaction with p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208615

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208615

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

100296

1039884704

0 references

100296

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15838523

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017