A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability (Q24297984)

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13 February 2020

title

A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability (English)

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13 February 2020

author

Diwakar R Pattabiraman

2

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13 February 2020

author name string

T Saether

1

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13 February 2020

A H Alm-Kristiansen

3

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13 February 2020

L T Vogt-Kielland

4

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13 February 2020

T J Gonda

5

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13 February 2020

O S Gabrielsen

6

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13 February 2020

language of work or name

English

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publication date

30 August 2010

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13 February 2020

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13 February 2020

volume

30

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13 February 2020

issue

2

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13 February 2020

page(s)

212-222

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The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb

13 February 2020

cites work

1 reference

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Concepts in sumoylation: a decade on

20 April 2017

1 reference

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Something about SUMO inhibits transcription

20 April 2017

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SUMO: a history of modification

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Modification of proteins by ubiquitin and ubiquitin-like proteins

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Ubc9 sumoylation regulates SUMO target discrimination

20 April 2017

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Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors

20 April 2017

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Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif

20 April 2017

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The mechanisms of PML-nuclear body formation

20 April 2017

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Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

20 April 2017

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Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

20 April 2017

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Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

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FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci

20 April 2017

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Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene

21 January 2018

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Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity

21 January 2018

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Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling.

21 January 2018

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Differential transcriptional activation by v-myb and c-myb in animal cells and Saccharomyces cerevisiae

21 January 2018

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The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

21 January 2018

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Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner

21 January 2018

1 reference

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Carboxy-terminal elements of c-Myb negatively regulate transcriptional activation in cis and in trans

21 January 2018

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Specific DNA binding by c-Myb: evidence for a double helix-turn-helix-related motif

21 January 2018

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Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae

21 January 2018

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Specification of SUMO1- and SUMO2-interacting motifs

21 January 2018

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Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

21 January 2018

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c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

21 January 2018

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The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors

21 January 2018

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

21 January 2018

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Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

21 January 2018

1 reference

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Transformation by v-myb correlates with trans-activation of gene expression

21 January 2018

1 reference

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A SUMO-regulated activation function controls synergy of c-Myb through a repressor-activator switch leading to differential p300 recruitment

21 January 2018

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Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types

21 January 2018

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Mutations in multiple domains of c-Myb disrupt interaction with CBP/p300 and abrogate myeloid transforming ability.

21 January 2018

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Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

21 January 2018

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MYB function in normal and cancer cells

21 January 2018

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Identification of a SUMO-binding motif that recognizes SUMO-modified proteins

21 January 2018

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Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation

21 January 2018

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Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins

21 January 2018

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The carboxyterminus of human c-myb protein stimulates activated transcription in trans

21 January 2018

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A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis

21 January 2018

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Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.

21 January 2018

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CBP as a transcriptional coactivator of c-Myb

31 March 2020

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Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro.

31 March 2020

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Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases

31 March 2020

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Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M

31 March 2020

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The chromatin remodeling factor Mi-2alpha acts as a novel co-activator for human c-Myb

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.397

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802522%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 February 2020

1010013970

0 references

1 reference