Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function (Q24298958)

C-abl oncogene 1, non-receptor tyrosine kinase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein ubiquitination

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2

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Valina L. Dawson

9

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Ted M. Dawson

10

object named as

Ted M Dawson

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author name string

Han Seok Ko

1

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Joo-Ho Shin

3

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Senthilkumar S Karuppagounder

4

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Bharathi Shrikanth Gadad

5

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Anthony J Koleske

6

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Olga Pletnikova

7

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Juan C Troncoso

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

21 September 2010

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published in

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volume

107

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issue

38

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page(s)

16691-6

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cites work

Dopamine covalently modifies and functionally inactivates parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity

19 March 2017

1 reference

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DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Identification of far upstream element-binding protein-1 as an authentic Parkin substrate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

19 March 2017

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The role of parkin in familial and sporadic Parkinson's disease

19 March 2017

1 reference

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Molecular pathogenesis of Parkinson disease: insights from genetic studies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Combined kinase inhibition modulates parkin inactivation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Diagnosis and treatment of Parkinson disease: molecules to medicine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Regulation of neuronal morphogenesis and synaptic function by Abl family kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944759

Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006083107

Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006083107

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006083107

Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20823226

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20823226

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1006083107

1 reference

959386

ADS bibcode

2010PNAS..10716691K

0 references

959386

1 reference

1 reference

1 reference