Amino acid residues in RAG1 responsible for the interaction with RAG2 during the V(D)J recombination process (Q24301696)

GOA release 2020-03-11

V(D)J recombination

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Jung Eun Ko

series ordinal

1

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Choong Won Kim

series ordinal

2

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Deok Ryong Kim

series ordinal

3

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language of work or name

English

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publication date

27 February 2004

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published in

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volume

279

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issue

9

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page(s)

7715-20

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cites work

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

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Sequences at the somatic recombination sites of immunoglobulin light-chain genes

21 January 2018

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

21 January 2018

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The V(D)J recombination activating gene, RAG-1.

21 January 2018

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Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311471200

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311471200

Initiation of V(D)J recombination in a cell-free system.

21 January 2018

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DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

21 January 2018

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 January 2018

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Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

21 January 2018

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Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

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Ku recruits the XRCC4-ligase IV complex to DNA ends

21 January 2018

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Initiation of V(D)J recombination in vitro obeying the 12/23 rule

21 January 2018

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Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

21 January 2018

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A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

21 January 2018

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RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

21 January 2018

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RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

21 January 2018

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A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

21 January 2018

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Assembly of the RAG1/RAG2 synaptic complex

21 January 2018

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RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

21 January 2018

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Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

21 January 2018

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Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

21 January 2018

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Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

21 January 2018

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Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex

21 January 2018

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Expression and V(D)J recombination activity of mutated RAG-1 proteins

21 January 2018

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Definition of a core region of RAG-2 that is functional in V(D)J recombination

21 January 2018

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Partial V(D)J recombination activity leads to Omenn syndrome

21 January 2018

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Functional analysis of coordinated cleavage in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311471200

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

21 January 2018

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Mammalian T-lymphocyte antigen receptor genes: genetic and nongenetic potential to generate variability

21 January 2018

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