Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter (Q24302387)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0038027

apolipoprotein A-I receptor activity

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0034188

Cell division cycle 42

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ATP binding cassette subfamily A member 1

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apolipoproteins E

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apolipoprotein C3

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Apolipoprotein A1

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apolipoprotein A-I receptor binding

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author

Arnold von Eckardstein

6

object named as

Arnold von Eckardstein

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Alan T. Remaley

2

object named as

Alan T Remaley

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author name string

Jerzy-Roch Nofer

1

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Renata Feuerborn

3

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Iza Wolinnska

4

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Thomas Engel

5

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Gerd Assmann

Journal of Lipid Research

7

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language of work or name

English

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publication date

April 2006

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published in

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volume

47

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issue

4

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page(s)

794-803

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cites work

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Tangier disease: still more questions than answers

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Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

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ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

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Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

21 January 2018

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ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.

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Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter

21 January 2018

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Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

21 January 2018

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Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol

21 January 2018

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Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.

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cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts

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Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

21 January 2018

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Involvement of Cdc42 signaling in apoA-I-induced cholesterol efflux

21 January 2018

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Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts

21 January 2018

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Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids

21 January 2018

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Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

21 January 2018

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Molecular interactions between apoE and ABCA1: impact on apoE lipidation

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Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway

21 January 2018

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Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides

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Importance of different pathways of cellular cholesterol efflux

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Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide

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Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis

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Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1.

21 January 2018

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Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids

21 January 2018

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Decreased expression of a member of the Rho GTPase family, Cdc42Hs, in cells from Tangier disease - the small G protein may play a role in cholesterol efflux

21 January 2018

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Defective cholesterol efflux in Werner syndrome fibroblasts and its phenotypic correction by Cdc42, a RhoGTPase

21 January 2018

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Current understanding of the role of high-density lipoproteins in atherosclerosis and senescence

21 January 2018

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ATP-binding cassette transporter-1 induces rearrangement of actin cytoskeletons possibly through Cdc42/N-WASP.

21 January 2018

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Molecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein

21 January 2018

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ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities

21 January 2018

1 reference

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Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux

21 January 2018

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The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500502-JLR200

Alpha1-syntrophin modulates turnover of ABCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500502-JLR200

Skeletal muscle signaling pathway through the dystrophin glycoprotein complex and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500502-JLR200

Apo AI/ABCA1-dependent and HDL3-mediated lipid efflux from compositionally distinct cholesterol-based microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M500502-JLR200

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

21 January 2018

1 reference

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Retarded intracellular lipid transport associated with reduced expression of Cdc42, a member of Rho-GTPases, in human aged skin fibroblasts: a possible function of Cdc42 in mediating intracellular lipid transport

21 January 2018

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