Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment (Q35203793)

7 August 2017

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title

Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment (English)

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7 August 2017

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7 August 2017

Arnold von Eckardstein

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Arnold von Eckardstein

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7 August 2017

language of work or name

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1 January 2003

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7 August 2017

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7 August 2017

63

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7 August 2017

18

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7 August 2017

1907-1945

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https://scigraph.springernature.com/pub.10.2165/00003495-200363180-00003

7 August 2017

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Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice

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12 December 2020

Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures

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12 December 2020

Stimulation of arterial endothelial cell prostacyclin synthesis by high density lipoproteins

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12 December 2020

The benefits of niacin in atherosclerosis

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12 December 2020

Gemfibrozil, nicotinic acid and combination therapy in patients with isolated hypoalphalipoproteinemia: a randomized, open-label, crossover study.

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12 December 2020

Dose-response effects of atorvastatin and simvastatin on high-density lipoprotein cholesterol in hypercholesterolaemic patients: a review of five comparative studies

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12 December 2020

Evidence that high-density lipoprotein cholesterol is an independent predictor of acute platelet-dependent thrombus formation.

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12 December 2020

17beta-Estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers.

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12 December 2020

Dissociation of lipid-free apolipoprotein A-I from high density lipoproteins

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12 December 2020

Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression

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12 December 2020

The Münster Heart Study (PROCAM): total mortality in middle-aged men is increased at low total and LDL cholesterol concentrations in smokers but not in nonsmokers

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12 December 2020

Apolipoprotein A-I and its amphipathic helix peptide analogues inhibit human immunodeficiency virus-induced syncytium formation

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12 December 2020

Regulation and activity of the human ABCA1 gene in transgenic mice

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12 December 2020

Oxysterols: friends, foes, or just fellow passengers?

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12 December 2020

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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12 December 2020

The terminal complement proteins C5b-9 augment binding of high density lipoprotein and its apolipoproteins A-I and A-II to human endothelial cells

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12 December 2020

Serum cholesterol efflux potential in postmenopausal monkeys treated with tibolone or conjugated estrogens.

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12 December 2020

Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter

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12 December 2020

High-density lipoprotein--the clinical implications of recent studies

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12 December 2020

Endothelium-dependent and -independent functions are impaired in patients with coronary heart disease

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12 December 2020

Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study

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12 December 2020

Protection against atherogenesis in mice mediated by human apolipoprotein A-IV

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12 December 2020

A molecular theory of lipid-protein interactions in the plasma lipoproteins

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12 December 2020

Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

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12 December 2020

Lipolyzed hypertriglyceridemic serum and triglyceride-rich lipoprotein cause lipid accumulation in and are cytotoxic to cultured human endothelial cells. High density lipoproteins inhibit this cytotoxicity

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12 December 2020

Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV.

1 reference

12 December 2020

Oxidized lipoproteins inhibit endothelium-dependent vasodilation. Effects of pressure and high-density lipoprotein

1 reference

12 December 2020

Endothelial lipase: a new member of the triglyceride lipase gene family

1 reference

12 December 2020

Decreased Susceptibility to Diet-Induced Atherosclerosis in Human Apolipoprotein A-II Transgenic Mice

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12 December 2020

High levels of human apolipoprotein A-I and high density lipoproteins in transgenic mice do not enhance efflux of cholesterol from a depot of injected lipoproteins. Relevance to regression of atherosclerosis?

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12 December 2020

Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular disease

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12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

1 reference

12 December 2020

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

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12 December 2020

TGF-beta increases cholesterol efflux and ABC-1 expression in macrophage-derived foam cells: opposing the effects of IFN-gamma.

1 reference

12 December 2020

NMR studies of lipoprotein structure

1 reference

12 December 2020

The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux

1 reference

12 December 2020

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits

1 reference

12 December 2020

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

12 December 2020

High density lipoprotein reverses inhibitory effect of oxidized low density lipoprotein on endothelium-dependent arterial relaxation

1 reference

12 December 2020

Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The Atherosclerosis Risk in Communities (ARIC) Study

1 reference

12 December 2020

Genetics and prevention: a new look at high-density lipoprotein cholesterol

1 reference

12 December 2020

Statin-fibrate combination therapy

1 reference

12 December 2020

Influence of low HDL on progression of coronary artery disease and response to fluvastatin therapy

1 reference

12 December 2020

High-dose recombinant apolipoprotein A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilization

1 reference

12 December 2020

Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study)

1 reference

12 December 2020

Pros and cons of inhibiting cholesteryl ester transfer protein

1 reference

12 December 2020

Oxidation of high density lipoproteins. II. Evidence for direct reduction of lipid hydroperoxides by methionine residues of apolipoproteins AI and AII

1 reference

12 December 2020

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice.

1 reference

12 December 2020

Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats. Correlation with physical properties

1 reference

12 December 2020

Increasing high-density lipoprotein cholesterol: an update on fenofibrate

1 reference

12 December 2020

Risk for diabetes mellitus in middle-aged Caucasian male participants of the PROCAM study: implications for the definition of impaired fasting glucose by the American Diabetes Association. Prospective Cardiovascular Münster.

1 reference

12 December 2020

Effect of dienogest-containing oral contraceptives on lipid metabolism

1 reference

12 December 2020

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

1 reference

12 December 2020

Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein

1 reference

12 December 2020

Lipoprotein responses to treatment with lovastatin, gemfibrozil, and nicotinic acid in normolipidemic patients with hypoalphalipoproteinemia

1 reference

12 December 2020

Testosterone dose-response relationships in healthy young men.

1 reference

12 December 2020

Cellular localization and trafficking of the human ABCA1 transporter

1 reference

12 December 2020

In VivoRegulation of Scavenger Receptor BI and the Selective Uptake of High Density Lipoprotein Cholesteryl Esters in Rat Liver Parenchymal and Kupffer Cells

1 reference

12 December 2020

Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione.

1 reference

12 December 2020

Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study

1 reference

12 December 2020

Paraoxonase and atherosclerosis

1 reference

12 December 2020

The in vitro formation of HDL2 during the action of LCAT: the role of triglyceride-rich lipoproteins.

1 reference

12 December 2020

Protective effect of high density lipoprotein on endothelium-dependent vasodilatation

1 reference

12 December 2020

Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease. Fibrate Consensus Group

1 reference

12 December 2020

CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors

1 reference

12 December 2020

Molecular biology and pathophysiological aspects of plasma cholesteryl ester transfer protein

1 reference

12 December 2020

Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol

1 reference

12 December 2020

Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group

1 reference

12 December 2020

Megalin and cubilin: multifunctional endocytic receptors

1 reference

12 December 2020

High-density lipoprotein restores endothelial function in hypercholesterolemic men.

1 reference

12 December 2020

Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat.

1 reference

12 December 2020

Inhibition of the lytic action of cell-bound terminal complement components by human high density lipoproteins and apoproteins

1 reference

12 December 2020

The effect of high density lipoprotein subfractions on endothelial eicosanoid secretion.

1 reference

12 December 2020

Nuclear receptors and lipid physiology: opening the X-files

1 reference

12 December 2020

Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia

1 reference

12 December 2020

Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I

1 reference

12 December 2020

The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein.

1 reference

12 December 2020

The myotoxicity of statins

1 reference

12 December 2020

Characterization of the effect of plasma lipoproteins on platelet function in vitro

1 reference

12 December 2020

Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study

1 reference

12 December 2020

HDL and apolipoprotein A-I protect erythrocytes against the generation of procoagulant activity

1 reference

12 December 2020

Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

1 reference

12 December 2020

Management of dyslipidemia

1 reference

12 December 2020

Low-dose estrogen supplementation improves vascular function in hypogonadal men.

1 reference

12 December 2020

Apical secretion of apolipoproteins from enterocytes

1 reference

12 December 2020

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

1 reference

12 December 2020

High-density lipoproteins differentially modulate cytokine-induced expression of E-selectin and cyclooxygenase-2

1 reference

12 December 2020

Deletion of the C-terminal domain of apolipoprotein A-I impairs cell surface binding and lipid efflux in macrophage

1 reference

12 December 2020

Action of atorvastatin in combined hyperlipidemia : preferential reduction of cholesteryl ester transfer from HDL to VLDL1 particles

1 reference

12 December 2020

Protein composition determines the anti-atherogenic properties of HDL in transgenic mice

1 reference

12 December 2020

Dose-dependent action of atorvastatin in type IIB hyperlipidemia: preferential and progressive reduction of atherogenic apoB-containing lipoprotein subclasses (VLDL-2, IDL, small dense LDL) and stimulation of cellular cholesterol efflux

1 reference

12 December 2020

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

1 reference

12 December 2020

Characterization of apoA-IV-containing lipoprotein particles isolated from human plasma and interstitial fluid.

1 reference

12 December 2020

Dissociation of high density lipoprotein precursors from apolipoprotein B-containing lipoproteins in the presence of unesterified fatty acids and a source of apolipoprotein A-I.

1 reference

12 December 2020

Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

1 reference

12 December 2020

Clinical efficacy and safety of cerivastatin: summary of pivotal phase IIb/III studies

1 reference

12 December 2020

Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein

1 reference

12 December 2020

Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia

1 reference

12 December 2020

Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may Be due to the abnormal composition of HDL.

1 reference

12 December 2020

Estrogen receptor-mediated repression of human hepatic lipase gene transcription.

1 reference

12 December 2020

Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology

1 reference

12 December 2020

Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia

1 reference

12 December 2020

High-density lipoprotein reduces epidermal growth factor-induced DNA synthesis in vascular smooth muscle cells

1 reference

12 December 2020

Lecithin cholesterol acyltransferase

1 reference

12 December 2020

The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo.

1 reference

12 December 2020

High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

1 reference

12 December 2020

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

1 reference

12 December 2020

1 reference

12 December 2020

Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice

1 reference

12 December 2020

Failure of estrogen plus progestin therapy for prevention

1 reference

12 December 2020

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

1 reference

12 December 2020

Peroxisome proliferator-activated receptor alpha is not rate-limiting for the lipoprotein-lowering action of fish oil.

1 reference

12 December 2020

Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial

1 reference

12 December 2020

Low density lipoprotein cholesterol and coronary microvascular dysfunction in hypercholesterolemia

1 reference

12 December 2020

Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study

1 reference

12 December 2020

Lipid-free apolipoprotein (apo) A-I is converted into alpha-migrating high density lipoproteins by lipoprotein-depleted plasma of normolipidemic donors and apo A-I-deficient patients but not of Tangier disease patients.

1 reference

12 December 2020

Novel polymorphisms in promoter region of atp binding cassette transporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response to therapy

1 reference

12 December 2020

Effect of niacin and etofibrate association on subjects with coronary artery disease and serum high-density lipoprotein cholesterol <35 mg/dl

1 reference

12 December 2020

Apolipoprotein-mediated removal of cellular cholesterol and phospholipids

1 reference

12 December 2020

Apolipoprotein E and atherosclerosis

1 reference

12 December 2020

Long-term effects of raloxifene on bone mineral density, bone turnover, and serum lipid levels in early postmenopausal women: three-year data from 2 double-blind, randomized, placebo-controlled trials

1 reference

12 December 2020

Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells

1 reference

12 December 2020

High-density lipoprotein and its apolipoproteins inhibit cytolytic activity of complement. Studies on the nature of inhibitory moiety

1 reference

12 December 2020

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI.

1 reference

12 December 2020

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

1 reference

12 December 2020

New perspectives on the management of low levels of high-density lipoprotein cholesterol

1 reference

12 December 2020

Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

1 reference

12 December 2020

Lipoprotein-induced prostacyclin production in endothelial cells and effects of lipoprotein modification

1 reference

12 December 2020

Complement C6 deficiency protects against diet-induced atherosclerosis in rabbits

1 reference

12 December 2020

Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice

1 reference

12 December 2020

Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells

1 reference

12 December 2020

Associations of obesity markers, insulin, and sex hormones with HDL-cholesterol levels in Turkish and German individuals

1 reference

12 December 2020

Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis

1 reference

12 December 2020

Orphan nuclear receptors find a home in the arterial wall

1 reference

12 December 2020

A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis.

1 reference

12 December 2020

Cell cholesterol efflux: integration of old and new observations provides new insights.

1 reference

12 December 2020

Value of HDL cholesterol, apolipoprotein A-I, lipoprotein A-I, and lipoprotein A-I/A-II in prediction of coronary heart disease: the PRIME Study. Prospective Epidemiological Study of Myocardial Infarction

1 reference

12 December 2020

High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma

1 reference

12 December 2020

The effects of mutations in helices 4 and 6 of ApoA-I on scavenger receptor class B type I (SR-BI)-mediated cholesterol efflux suggest that formation of a productive complex between reconstituted high density lipoprotein and SR-BI is required for ef

1 reference

12 December 2020

Binding of apoE-rich high density lipoprotein particles by saturable sites on human blood platelets inhibits agonist-induced platelet aggregation

1 reference

12 December 2020

An ecological study of determinants of coronary heart disease rates: a comparison of Czech, Bavarian and Israeli men.

1 reference

12 December 2020

A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction

1 reference

12 December 2020

Does paraoxonase play a role in susceptibility to cardiovascular disease?

1 reference

12 December 2020

Comparison of the lipoprotein, carbohydrate, and hemostatic effects of phasic oral contraceptives containing desogestrel or levonorgestrel.

1 reference

12 December 2020

Atherosclerosis. the road ahead

1 reference

12 December 2020

The paraoxonase gene family and coronary heart disease

1 reference

12 December 2020

Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S.

1 reference

12 December 2020

Tangier disease: a disorder of intracellular membrane traffic

1 reference

12 December 2020

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

1 reference

12 December 2020

HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate.

1 reference

12 December 2020

Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice

1 reference

12 December 2020

Efficacy of combination of atorvastatin and micronised fenofibrate in the treatment of severe mixed hyperlipidemia

1 reference

12 December 2020

Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Tr

1 reference

12 December 2020

Phospholipid transfer protein mediated conversion of high density lipoproteins generates pre beta 1-HDL

1 reference

12 December 2020

Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II)

1 reference

12 December 2020

Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.

1 reference

12 December 2020

Current perspectives on statins

1 reference

12 December 2020

Endogenous apolipoprotein E modulates cholesterol efflux and cholesteryl ester hydrolysis mediated by high-density lipoprotein-3 and lipid-free apolipoproteins in mouse peritoneal macrophages

1 reference

12 December 2020

Interferon-gamma-mediated downregulation of cholesterol efflux and ABC1 expression is by the Stat1 pathway

1 reference

12 December 2020

Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease

1 reference

12 December 2020

Mechanism of action of niacin on lipoprotein metabolism

1 reference

12 December 2020

Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II.

1 reference

12 December 2020

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

1 reference

12 December 2020

The aggregation of isolated human platelets in the presence of lipoproteins and prostacyclin

1 reference

12 December 2020

Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A.

1 reference

12 December 2020

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene

1 reference

12 December 2020

Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene

1 reference

12 December 2020

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group

1 reference

12 December 2020

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

12 December 2020

Enhanced tissue factor activity and plasminogen activator inhibitor-1 antigen in human umbilical vein endothelial cells incubated with lipoproteins

1 reference

12 December 2020

The cellular biology of scavenger receptor class B type I

1 reference

12 December 2020

High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis

1 reference

12 December 2020

Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term Study.

1 reference

12 December 2020

Concentrations of electrophoretic and size subclasses of apolipoprotein A-I-containing particles in human peripheral lymph

1 reference

12 December 2020

Increased prebeta-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes

1 reference

12 December 2020

Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells

1 reference

12 December 2020

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

1 reference

12 December 2020

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

1 reference

12 December 2020

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

1 reference

12 December 2020

Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries

1 reference

12 December 2020

A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men.

1 reference

12 December 2020

High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase

1 reference

12 December 2020

Apo A-I inhibits foam cell formation in Apo E-deficient mice after monocyte adherence to endothelium

1 reference

12 December 2020

Effect of very-low-dose niacin on high-density lipoprotein in patients undergoing long-term statin therapy

1 reference

12 December 2020

The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: evidence for particle fusion

1 reference

12 December 2020

Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine

1 reference

12 December 2020

Dietary n-3 polyunsaturated fat increases the fractional catabolic rate of medium-sized HDL particles in African green monkeys

1 reference

12 December 2020

Oxidized lipids as mediators of coronary heart disease

1 reference

12 December 2020

Epidemiological aspects of high density lipoprotein cholesterol.

1 reference

12 December 2020

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

1 reference

12 December 2020

Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse

1 reference

12 December 2020

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

1 reference

12 December 2020

Activation of phosphatidylinositol-specific phospholipase C by HDL-associated lysosphingolipid. Involvement in mitogenesis but not in cholesterol efflux

1 reference

12 December 2020

Inhibition of VCAM-1 Expression in Endothelial Cells by Reconstituted High Density Lipoproteins

1 reference

12 December 2020

Increased prebeta-HDL levels, cholesterol efflux, and LCAT-mediated esterification in mice expressing the human cholesteryl ester transfer protein (CETP) and human apolipoprotein A-I (apoA-I) transgenes

1 reference

12 December 2020

Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models

1 reference

12 December 2020

Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease

1 reference

12 December 2020

Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1.

1 reference

12 December 2020

Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI.

1 reference

12 December 2020

Antiviral effects of apolipoprotein A-I and its synthetic amphipathic peptide analogs

1 reference

12 December 2020

ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

1 reference

12 December 2020

The ATP binding cassette transporter A1 contributes to the secretion of interleukin 1beta from macrophages but not from monocytes

1 reference

12 December 2020

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

12 December 2020

Hepatic lipase: new insights from genetic and metabolic studies

1 reference

12 December 2020

Cholesterol efflux potential of sera from mice expressing human cholesteryl ester transfer protein and/or human apolipoprotein AI

1 reference

12 December 2020

Remodelling of high density lipoproteins by plasma factors

1 reference

12 December 2020

ATP-binding cassette transporter A1 and cholesterol trafficking

1 reference

12 December 2020

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages

1 reference

12 December 2020

High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion

1 reference

12 December 2020

Endothelial function and atherosclerosis.

1 reference

12 December 2020

Identification of persons at high risk for type 2 diabetes mellitus: do we need the oral glucose tolerance test?

1 reference

12 December 2020

Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin

1 reference

12 December 2020

Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice

1 reference

12 December 2020

ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte-derived macrophages.

1 reference

12 December 2020

Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism

1 reference

12 December 2020

Regulation and intracellular trafficking of the ABCA1 transporter

1 reference

12 December 2020

High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport

1 reference

12 December 2020

Short-term prognostic value of lipid measurements in patients with angina pectoris. The ECAT Angina Pectoris Study Group: European Concerted Action on Thrombosis and Disabilities

1 reference

12 December 2020

Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1.

1 reference

12 December 2020

The impact of phospholipid transfer protein (PLTP) on HDL metabolism

1 reference

12 December 2020

Platelet interaction with high and low density lipoproteins

1 reference

12 December 2020

The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism

1 reference

12 December 2020

Effect of pravastatin on coronary disease events in subgroups defined by coronary risk factors: the Prospective Pravastatin Pooling Project

1 reference

12 December 2020

Increased ABCA1 activity protects against atherosclerosis.

1 reference

12 December 2020

Oral estrogen replacement therapy in postmenopausal women selectively raises levels and production rates of lipoprotein A-I and lowers hepatic lipase activity without lowering the fractional catabolic rate

1 reference

12 December 2020

Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia

1 reference

12 December 2020

Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial

1 reference

12 December 2020

Inhibitory effect of high-density lipoprotein on platelet function is mediated by increase in nitric oxide synthase activity in platelets

1 reference

12 December 2020

Physiological role and clinical relevance of high-density lipoprotein subclasses

1 reference

12 December 2020

Binding of apolipoprotein A-I model peptides to lipid bilayers. Measurement of binding isotherms and peptide-lipid headgroup interactions

1 reference

12 December 2020

Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

1 reference

12 December 2020

Prevention of coronary heart disease by raising high-density lipoprotein cholesterol?

1 reference

12 December 2020

Secretion of pre-beta-migrating apoA-I by cynomolgus monkey hepatocytes in culture

1 reference

12 December 2020

Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes

1 reference

12 December 2020

Atherosclerotic disease in marked hyperalphalipoproteinemia. Combined reduction of cholesteryl ester transfer protein and hepatic triglyceride lipase

1 reference

12 December 2020

Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities

1 reference

12 December 2020

Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux

1 reference

12 December 2020

Tibolone lowers high density lipoprotein cholesterol by increasing hepatic lipase activity but does not impair cholesterol efflux

1 reference

12 December 2020

Effects of high-density lipoprotein on acetylcholine-induced coronary vasoreactivity

1 reference

12 December 2020

HDL and ApoA prevent cell death of endothelial cells induced by oxidized LDL

1 reference

12 December 2020

High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.

1 reference

12 December 2020

Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol

1 reference

12 December 2020

n-3 fatty acids and lipoproteins: comparison of results from human and animal studies

1 reference

12 December 2020

Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients

1 reference

12 December 2020

Regulation of the concentration of pre beta high-density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltransferase activity

1 reference

12 December 2020

Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes.

1 reference

12 December 2020

Hepatic lipase induces the formation of pre-beta 1 high density lipoprotein (HDL) from triacylglycerol-rich HDL2. A study comparing liver perfusion to in vitro incubation with lipases

1 reference

12 December 2020

A broad role for the zinc finger protein ZNF202 in human lipid metabolism

1 reference

12 December 2020

Identification and characterization of LRP8 (apoER2) in human blood platelets

1 reference

12 December 2020

Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Lopid Coronary Angiography Trial (LOCAT) Study Group

1 reference

12 December 2020

Paraoxonase and coronary heart disease

1 reference

12 December 2020

Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

1 reference

12 December 2020

Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice

1 reference

12 December 2020

Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

1 reference

12 December 2020

Interaction between apolipoproteins A-I and A-II and the membrane attack complex of complement. Affinity of the apoproteins for polymeric C9.

1 reference

12 December 2020

Stable isotope turnover of apolipoproteins of high-density lipoproteins in humans

1 reference

12 December 2020

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

1 reference

12 December 2020

High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

1 reference

12 December 2020

Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

1 reference

12 December 2020

Increased risk of myocardial infarction in men with both hypertriglyceridemia and elevated HDL cholesterol

1 reference

12 December 2020

High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules

1 reference

12 December 2020

Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety

1 reference

12 December 2020

Effects of Nicotinic Acid Therapy on Plasma High Density Lipoprotein Subfraction Distribution and Composition and on Apolipoprotein A Metabolism

1 reference

12 December 2020

Arrangement of apolipoprotein A-I in reconstituted high-density lipoprotein disks: an alternative model based on fluorescence resonance energy transfer experiments

1 reference

12 December 2020

Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice

1 reference

12 December 2020

Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)

1 reference

12 December 2020

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

1 reference

12 December 2020

Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1.

1 reference

12 December 2020

Effect of human native low-density and high-density lipoproteins on prostaglandin production by mouse macrophage cell line P388D1: possible implications in pathogenesis of atherosclerosis

1 reference

12 December 2020

Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids

1 reference

12 December 2020

Apolipoprotein-mediated plasma membrane microsolubilization. Role of lipid affinity and membrane penetration in the efflux of cellular cholesterol and phospholipid

1 reference

12 December 2020

Cubilin, a multifunctional epithelial receptor: an overview.

1 reference

12 December 2020

Remodelling of reconstituted high density lipoproteins by lecithin: cholesterol acyltransferase.

1 reference

12 December 2020

Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages

1 reference

12 December 2020

Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene

1 reference

12 December 2020

High density lipoproteins enhance the Na+/H+ antiport in human platelets

1 reference

12 December 2020

Comparison of apo A-I-containing subpopulations of dog plasma and prenodal peripheral lymph: evidence for alteration in subpopulations in the interstitial space

1 reference

12 December 2020

BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

1 reference

12 December 2020

Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

The structural basis for amyloid formation by plasma apolipoproteins: a review

1 reference

12 December 2020

Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile

1 reference

12 December 2020

Adenovirus-mediated rescue of lipoprotein lipase-deficient mice. Lipolysis of triglyceride-rich lipoproteins is essential for high density lipoprotein maturation in mice

1 reference

12 December 2020

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

1 reference

12 December 2020

Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma

1 reference

12 December 2020

HDL and arteriosclerosis: beyond reverse cholesterol transport

1 reference

12 December 2020

Androgens and coronary artery disease

1 reference

12 December 2020

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

1 reference

12 December 2020

Mechanism of accumulation of cholesterol and cholestanol in tendons and the role of sterol 27-hydroxylase (CYP27A1)

1 reference

12 December 2020

Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)

1 reference

12 December 2020

Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway

1 reference

12 December 2020

Lowering of HDL cholesterol in post-menopausal women by tibolone is not associated with changes in cholesterol efflux capacity or paraoxonase activity

1 reference

12 December 2020

Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport

1 reference

12 December 2020

Detailed molecular model of apolipoprotein A-I on the surface of high-density lipoproteins and its functional implications.

1 reference

12 December 2020

Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells

1 reference

12 December 2020

Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment

1 reference

12 December 2020

Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial

1 reference

12 December 2020

Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study.

1 reference

12 December 2020

Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis

1 reference

12 December 2020

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

1 reference

12 December 2020

Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome

1 reference

12 December 2020

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol

1 reference

12 December 2020

HDL-Induced Prostacyclin Release in Smooth Muscle Cells Is Dependent on Cyclooxygenase-2 (Cox-2)

1 reference

12 December 2020

Cellular cholesterol flux studies: methodological considerations

1 reference

12 December 2020

Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency

1 reference

12 December 2020

Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet

1 reference

12 December 2020

1999 George Lyman Duff memorial lecture: lipid transfer proteins, HDL metabolism, and atherogenesis

1 reference

12 December 2020

Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide

1 reference

12 December 2020

n-3 Fatty acids from fish and fish oil: panacea or nostrum?

1 reference

12 December 2020

Molecular basis of autosomal-dominant polycystic kidney disease

1 reference

12 December 2020

Molecular physiology of reverse cholesterol transport

1 reference

12 December 2020

Isolation and partial characterization of the inactive and active forms of human plasma phospholipid transfer protein (PLTP).

1 reference

12 December 2020

Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux

1 reference

12 December 2020

Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans

1 reference

12 December 2020

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women

1 reference

12 December 2020

Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phase

1 reference

12 December 2020

Prevalence of risk factors in men with premature coronary artery disease

1 reference

12 December 2020

Anticoagulant activity of tissue factor pathway inhibitor in human plasma is preferentially associated with dense subspecies of LDL and HDL and with Lp(a)

1 reference

12 December 2020

Hepatic lipase and HDL metabolism

1 reference

12 December 2020

PPARadigms and PPARadoxes: expanding roles for PPARgamma in the control of lipid metabolism.

1 reference

12 December 2020

Pre-beta HDL: structure and metabolism

1 reference

12 December 2020

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice

1 reference

12 December 2020

Inhibition of Atherosclerosis Development in Cholesterol-Fed Human Apolipoprotein A-I–Transgenic Rabbits

1 reference

12 December 2020

Effects of lipids and lipoproteins on thrombosis and rheology.

1 reference

12 December 2020

A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells

1 reference

12 December 2020

The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation

1 reference

12 December 2020

10.2165/00003495-200363180-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference