Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway (Q24303511)

GOA release 2020-03-11

protein phosphorylation

1 reference

GOA release 2020-03-11

author name string

Donghwa Kim

1

0 references

Shaokun Shu

2

0 references

Marc D Coppola

3

0 references

Satoshi Kaneko

4

0 references

Zeng-Qiang Yuan

5

0 references

Jin Q Cheng

Creative Commons Attribution 4.0 International

6

0 references

language of work or name

English

0 references

publication date

2010

0 references

published in

PLOS One

0 references

volume

5

0 references

page(s)

e9616

0 references

issue

3

0 references

copyright license

start time

9 March 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

19 March 2017

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The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1

19 March 2017

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RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

19 March 2017

1 reference

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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

19 March 2017

1 reference

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

19 March 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

19 March 2017

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Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

19 March 2017

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Newly identified stress-responsive protein kinases, Krs-1 and Krs-2

19 March 2017

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Cloning and characterization of a member of the MST subfamily of Ste20-like kinases

19 March 2017

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Cloning and characterization of a human protein kinase with homology to Ste20

19 March 2017

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

19 March 2017

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Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

19 March 2017

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Identification of a novel Ras-regulated proapoptotic pathway

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Regulation of cell death protease caspase-9 by phosphorylation

19 March 2017

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Cellular survival: a play in three Akts

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Elucidation of a universal size-control mechanism in Drosophila and mammals

7 April 2017

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FOXO transcription factors at the interface between longevity and tumor suppression

7 April 2017

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

7 April 2017

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

7 April 2017

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Hippo pathway-dependent and -independent roles of RASSF6.

7 April 2017

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The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.

27 September 2017

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NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis

27 September 2017

1 reference

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Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation

27 September 2017

1 reference

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Filling out the Hippo pathway

27 September 2017

1 reference

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RETRACTED: Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212

27 September 2017

1 reference

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Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

27 September 2017

1 reference

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Binding and phosphorylation of par-4 by akt is essential for cancer cell survival.

27 September 2017

1 reference

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Taming the Hippo: Raf-1 controls apoptosis by suppressing MST2/Hippo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Nicotine inactivation of the proapoptotic function of Bax through phosphorylation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Signaling by the germinal center kinase family of protein kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2834758

Cell Death in Development

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20231902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell signaling: life or death decisions of ras proteins

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1371/JOURNAL.PONE.0009616

Identifiers

DOI

10.1371/JOURNAL.PONE.0009616

1 reference

691260

ADS bibcode

2010PLoSO...5.9616K

0 references

691260

1 reference

1 reference

1 reference