The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7 (Q24306662)

negative regulation of protein ubiquitination

GOA release 2020-03-11

1 reference

Activation of innate immune antiviral responses by Nod2

GOA release 2020-03-11

2

Joseph S Pagano

0 references

author name string

Shunbin Ning

series ordinal

1

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language of work or name

English

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publication date

June 2010

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published in

Journal of Virology

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volume

84

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issue

12

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page(s)

6130-8

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cites work

1 reference

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

19 March 2017

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

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BS69 negatively regulates the canonical NF-kappaB activation induced by Epstein-Barr virus-derived LMP1

19 March 2017

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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

19 March 2017

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Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence

19 March 2017

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Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytes

19 March 2017

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

19 March 2017

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A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter

19 March 2017

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

19 March 2017

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

19 March 2017

1 reference

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Interferon regulatory factor 7 regulates expression of Epstein-Barr virus latent membrane protein 1: a regulatory circuit

19 March 2017

1 reference

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IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency

19 March 2017

1 reference

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Interferon-inducible antiviral effectors

19 March 2017

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RING domain E3 ubiquitin ligases

19 March 2017

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DUBA: a deubiquitinase that regulates type I interferon production

19 March 2017

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Breaking the chains: structure and function of the deubiquitinases

19 March 2017

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Interferons at age 50: past, current and future impact on biomedicine

19 March 2017

1 reference

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Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of Irf7

19 March 2017

1 reference

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IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

19 March 2017

1 reference

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The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein

19 March 2017

1 reference

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The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

19 March 2017

1 reference

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Negative regulation of Toll-like-receptor signaling by IRF-4.

19 March 2017

1 reference

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Physiological functions of the HECT family of ubiquitin ligases

19 March 2017

1 reference

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Nonproteolytic functions of ubiquitin in cell signaling

7 April 2017

1 reference

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Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

7 April 2017

1 reference

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Type I interferons in host defense

7 April 2017

1 reference

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

7 April 2017

1 reference

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Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

7 April 2017

1 reference

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Expression and functional studies of ubiquitin C-terminal hydrolase L1 regulated genes

27 September 2017

1 reference

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Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity

27 September 2017

1 reference

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TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

27 September 2017

1 reference

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RIG-I-like receptors: sensing and responding to RNA virus infection

27 September 2017

1 reference

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Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling

27 September 2017

1 reference

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Functional analysis of a dominant negative mutation of interferon regulatory factor 5

27 September 2017

1 reference

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TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

27 September 2017

1 reference

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Ubiquitylation in innate and adaptive immunity.

27 September 2017

1 reference

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The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity.

27 September 2017

1 reference

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Interferons: signaling, antiviral and viral evasion

27 September 2017

1 reference

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HSV ICP0 recruits USP7 to modulate TLR-mediated innate response

27 September 2017

1 reference

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Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis

27 September 2017

1 reference

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Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies

27 September 2017

1 reference

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TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Deubiquitylation and regulation of the immune response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Role of the ubiquitin system and tumor viruses in AIDS-related cancer

27 September 2017

1 reference

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IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Manipulation of the toll-like receptor 7 signaling pathway by Epstein-Barr virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Toll-like receptors in systemic autoimmune disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

The latent membrane protein 1 of Epstein-Barr virus (EBV) primes EBV latency cells for type I interferon production

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Targeting of host-cell ubiquitin pathways by viruses

27 September 2017

1 reference

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Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.

27 September 2017

1 reference

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A20 is a negative regulator of IFN regulatory factor 3 signaling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Regulation of expression of the Epstein-Barr virus BamHI-A rightward transcripts.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Functional dichotomy of A20 in apoptotic and necrotic cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitination

27 September 2017

1 reference

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Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Epstein-Barr virus latent membrane protein 1: structure and functions

27 September 2017

1 reference

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Interferon regulatory factor 7 mediates activation of Tap-2 by Epstein-Barr virus latent membrane protein 1.

27 September 2017

1 reference

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Interferon regulatory factor 7 is induced by Epstein-Barr virus latent membrane protein 1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Interferon regulatory factor 2 represses the Epstein-Barr virus BamHI Q latency promoter in type III latency

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency

27 September 2017

1 reference

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Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene.

27 September 2017

1 reference

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Epstein-barr virus encodes three bona fide ubiquitin-specific proteases

27 September 2017

1 reference

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Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876664

The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B

30 May 2018

1 reference

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Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis.

30 May 2018

1 reference

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29 November 2018

Viruses and lymphomas

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The A20 protein interacts with the Epstein-Barr virus latent membrane protein 1 (LMP1) and alters the LMP1/TRAF1/TRADD complex

29 November 2018

1 reference

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LMP1 signaling and activation of NF-kappaB in LMP1 transgenic mice

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20392859