Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1 (Q24307986)

positive regulation of establishment of protein localization to telomere

GO:1904871

1 reference

negative regulation of protein localization to Cajal body

GO:1904851

1 reference

telomerase RNA stabilization

GO:1904870

1 reference

protein localization to Cajal body

GO:0090669

1 reference

regulation of protein localization to Cajal body

GO:1904867

1 reference

negative regulation of telomerase RNA localization to Cajal body

GO:1904869

1 reference

positive regulation of telomerase RNA localization to Cajal body

GO:1904873

2 references

GO:1904874

regulation of telomerase RNA localization to Cajal body

GOA release 2020-03-11

1 reference

telomerase RNA localization

GO:1904872

1 reference

RNA localization to Cajal body

GO:0090672

1 reference

scaRNA localization to Cajal body

GO:0090670

1 reference

telomerase RNA localization to Cajal body

GO:0090666

1 reference

negative regulation of establishment of protein localization to telomere

GO:0090671

1 reference

6

Judith Frydman

0 references

Franklin L Zhong

object named as

Franklin L Zhong

2

1 reference

ORCID Public Data File 2021

Steven E Artandi

7

object named as

Steven E Artandi

0 references

author name string

Adam Freund

1

0 references

Andrew S Venteicher

3

0 references

Zhaojing Meng

4

0 references

Timothy D Veenstra

5

0 references

language of work or name

English

0 references

publication date

4 December 2014

0 references

published in

Cell

0 references

volume

159

0 references

issue

6

0 references

page(s)

1389-403

0 references

cites work

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Aging as an event of proteostasis collapse

19 March 2017

1 reference

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TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

19 March 2017

1 reference

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Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs

19 March 2017

1 reference

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A telomerase component is defective in the human disease dyskeratosis congenita

19 March 2017

1 reference

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Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Systems analyses reveal two chaperone networks with distinct functions in eukaryotic cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Functional requirement of p23 and Hsp90 in telomerase complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Protein composition of catalytically active human telomerase from immortal cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Creation of human tumour cells with defined genetic elements

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Molecular chaperones in protein folding and proteostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Highly recurrent TERT promoter mutations in human melanoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

TERT promoter mutations in familial and sporadic melanoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

How shelterin protects mammalian telomeres

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Differential scales of protein quality control

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Understanding telomere diseases through analysis of patient-derived iPS cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

In situ visualization of telomere elongation patterns in human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Many disease-associated variants of hTERT retain high telomerase enzymatic activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Molecular chaperone functions in protein folding and proteostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Replication of telomeres and the regulation of telomerase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Specificity requirements for human telomere protein interaction with telomerase holoenzyme

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Biogenesis of telomerase ribonucleoproteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Telomerase recruitment requires both TCAB1 and Cajal bodies independently

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Telomeres and telomerase in cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Two families of chaperonin: physiology and mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Telomere length homeostasis requires that telomerase levels are limiting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

A cytoplasmic chaperonin that catalyzes beta-actin folding

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329143

Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25467444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25467444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.10.059