BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer (Q24310192)

GOA release 2020-03-11

regulation of cell cycle

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International Journal of Cancer

GOA release 2020-03-11

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1

Ali Naderi

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Ian C. Bennett

object named as

Ian C Bennett

series ordinal

3

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author name string

Ji Liu

series ordinal

2

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language of work or name

English

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publication date

1 April 2010

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published in

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volume

126

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issue

7

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page(s)

1596-610

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cites work

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NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

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Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells

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Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat.

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Expression of the NF-κB targets BCL2 and BIRC5/Survivin characterizes small B-cell and aggressive B-cell lymphomas, respectively

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Mitochondrial ceramide and the induction of apoptosis

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Loss of cyclin A and G1-cell cycle arrest are a prerequisite of ceramide-induced toxicity in human arterial endothelial cells.

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Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA.

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Involvement of p27(kip1) in ceramide-mediated apoptosis in HL-60 cells

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Ceramide in the eukaryotic stress response

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Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathway

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Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

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PP2A fulfills its promises as tumor suppressor: which subunits are important?

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Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling

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Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells

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Ceramide triggers an NF-kappaB-dependent survival pathway through calpain.

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Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy

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Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.

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Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks

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Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.

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A gene-expression signature to predict survival in breast cancer across independent data sets.

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cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells

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Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.

1 reference

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

1 reference

7 January 2021

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

1 reference

7 January 2021

Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A

1 reference

7 January 2021

Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

1 reference

7 January 2021

Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis

1 reference

7 January 2021

Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria

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7 January 2021

Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways

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7 January 2021

Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins

1 reference

7 January 2021

Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic activity of nerve growth factor in breast cancer cells

1 reference

7 January 2021

Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation.

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7 January 2021

Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

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Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements

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Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells

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Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.

1 reference

7 January 2021

BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines

1 reference

7 January 2021

The nuclear transcription factor kappaB/bcl-2 pathway correlates with pathologic complete response to doxorubicin-based neoadjuvant chemotherapy in human breast cancer.

1 reference

7 January 2021

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice

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7 January 2021

Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding

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7 January 2021

Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications

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7 January 2021

Identifiers

DOI

10.1002/IJC.24866

1 reference

Consolidated OpenCitations Corpus – April 2017

release_try74wunm5hbdchtbt2iv6xkny

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/try74wunm5hbdchtbt2iv6xkny

24 November 2022

mapped directly with Wikidata item

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

19711341

1 reference

Consolidated OpenCitations Corpus – April 2017