Ceramide triggers an NF-kappaB-dependent survival pathway through calpain. (Q40413936)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15933726%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Ceramide triggers an NF-kappaB-dependent survival pathway through calpain (English)

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12 January 2020

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1

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12 January 2020

author name string

Bertoli C

series ordinal

2

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12 January 2020

Greer PA

series ordinal

3

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12 January 2020

Schneider C

series ordinal

4

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12 January 2020

publication date

1 May 2005

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Cell Death & Differentiation

12 January 2020

published in

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12 January 2020

volume

12

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12 January 2020

issue

5

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12 January 2020

page(s)

512-522

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401592

12 January 2020

exact match

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease

21 January 2018

1 reference

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Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

21 January 2018

1 reference

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Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha

21 January 2018

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Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3)

21 January 2018

1 reference

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The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

21 January 2018

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7 January 2021

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

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7 January 2021

Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades

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7 January 2021

Phosphorylation of Raf by ceramide-activated protein kinase

1 reference

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7 January 2021

Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I

1 reference

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7 January 2021

C2-ceramide as a cell death inducer in HC11 mouse mammary epithelial cells

1 reference

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7 January 2021

Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells

1 reference

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7 January 2021

Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression.

1 reference

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7 January 2021

Pituitary adenylate cyclase‐activating polypeptide prevents C2‐ceramide‐induced apoptosis of cerebellar granule cells

1 reference

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7 January 2021

Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells.

1 reference

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7 January 2021

Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells

1 reference

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7 January 2021

Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase

1 reference

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7 January 2021

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

1 reference

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7 January 2021

Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells

1 reference

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7 January 2021

Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity

1 reference

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7 January 2021

Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes

1 reference

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7 January 2021

Role of nuclear factor-kappaB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells

1 reference

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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7 January 2021

Shaping the nuclear action of NF-kappaB

1 reference

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7 January 2021

Missing pieces in the NF-kappaB puzzle

1 reference

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7 January 2021

Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2A

1 reference

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7 January 2021

Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Tumor necrosis factor-alpha induces distinctive NF-kappa B signaling within human dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Regulation of cell migration by the calcium-dependent protease calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway

1 reference

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7 January 2021

Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

1 reference

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7 January 2021

Killing tumours by ceramide-induced apoptosis: a critique of available drugs

1 reference

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7 January 2021

Ceramide activates NFkappaB by inducing the processing of p105.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Proteolytic processing of beta-amyloid precursor by calpain I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

A p105-based inhibitor broadly represses NF-kappa B activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism

1 reference

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7 January 2021

Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells

1 reference

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7 January 2021

Ceramide synthesis and metabolism as a target for cancer therapy.

1 reference

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7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

NF-kappaB in cancer: a marked target

1 reference

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7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Chemical approaches to angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

p105.Ikappa Bgamma and prototypical Ikappa Bs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401592

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401592

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15933726%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

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