Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1 (Q24310373)

DNA topoisomerase II alpha

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Phospholipid scramblase 1

1 reference

enzyme binding

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Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression

4

Susan P C Cole

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author name string

Jessica P Wyles

series ordinal

1

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Zhongqin Wu

series ordinal

2

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Shelagh E L Mirski

series ordinal

3

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language of work or name

English

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publication date

2007

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published in

Nucleic Acids Research

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volume

35

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issue

12

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page(s)

4076-85

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cites work

1 reference

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Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE))

19 March 2017

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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis

19 March 2017

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Histone deacetylase interacts directly with DNA topoisomerase II

19 March 2017

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DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

19 March 2017

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Modulation of human DNA topoisomerase IIalpha function by interaction with 14-3-3epsilon

19 March 2017

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Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53

19 March 2017

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A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator

19 March 2017

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Structure and function of type II DNA topoisomerases

19 March 2017

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Cellular roles of dna topoisomerases: a molecular perspective

19 March 2017

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Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation

19 March 2017

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Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha

19 March 2017

1 reference

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Palmitoylation of intracellular signaling proteins: regulation and function

19 March 2017

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Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta

19 March 2017

1 reference

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Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane

19 March 2017

1 reference

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Suppression of ovarian carcinoma cell growth in vivo by the interferon-inducible plasma membrane protein, phospholipid scramblase 1

19 March 2017

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Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon-alpha

19 March 2017

1 reference

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DNA topoisomerase IIbeta and neural development

19 March 2017

1 reference

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Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain

19 March 2017

1 reference

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C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo

19 March 2017

1 reference

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Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells

27 September 2017

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The topoisomerase II-Hsp90 complex: a new chemotherapeutic target?

27 September 2017

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Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme

27 September 2017

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Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals

27 September 2017

1 reference

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Phospholipid scramblase 1 is imported into the nucleus by a receptor-mediated pathway and interacts with DNA.

27 September 2017

1 reference

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Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils

27 September 2017

1 reference

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Catalytic topoisomerase II inhibitors in cancer therapy.

27 September 2017

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Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha

27 September 2017

1 reference

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Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells

27 September 2017

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Tumor cell death induced by topoisomerase-targeting drugs.

27 September 2017

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Induction of apoptosis by cancer chemotherapy.

27 September 2017

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A truncated cytoplasmic topoisomerase IIalpha in a drug-resistant lung cancer cell line is encoded by a TOP2A allele with a partial deletion of exon 34.

27 September 2017

1 reference

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Functional interaction between human topoisomerase IIalpha and retinoblastoma protein

27 September 2017

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Structural organization of the human TOP2A and TOP2B genes.

27 September 2017

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Loss of amino acids 1490Lys-Ser-Lys1492 in the COOH-terminal region of topoisomerase IIalpha in human small cell lung cancer cells selected for resistance to etoposide results in an extranuclear enzyme localization.

27 September 2017

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Role of topoisomerase II beta in the resistance of 9-OH-ellipticine-resistant Chinese hamster fibroblasts to topoisomerase II inhibitors

27 September 2017

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TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines

27 September 2017

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Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae

27 September 2017

1 reference

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Cytoplasmic localization of a mutant M(r) 160,000 topoisomerase II alpha is associated with the loss of putative bipartite nuclear localization signals in a drug-resistant human lung cancer cell line

27 September 2017

1 reference

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Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line.

27 September 2017

1 reference

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Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

27 September 2017

1 reference

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MmTRA1b/phospholipid scramblase 1 gene expression is a new prognostic factor for acute myelogenous leukemia.

30 May 2018

1 reference

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Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta

29 November 2018

1 reference

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Involvement of DNA topoisomerase IIbeta in neuronal differentiation

29 November 2018

1 reference

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Sequence determinants of nuclear localization in the alpha and beta isoforms of human topoisomerase II.

29 November 2018

1 reference

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Human DNA topoisomerases II alpha and II beta can functionally substitute for yeast TOP2 in chromosome segregation and recombination.

29 November 2018

1 reference

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Mitotic phosphorylation of DNA topoisomerase II alpha by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469

29 November 2018

1 reference

12 December 2020

The topoisomerase II-associated protein, Pat1p, is required for maintenance of rDNA locus stability in Saccharomyces cerevisiae

1 reference

12 December 2020

Recruitment of cdc2 kinase by DNA topoisomerase II is coupled to chromatin remodeling

1 reference

12 December 2020

Epitope distribution of randomly established monoclonal antibodies against human type II DNA topoisomerases

1 reference

12 December 2020

Modification of DNA topoisomerase II activity via direct interactions with the cyclic adenosine-3',5'-monophosphate response element-binding protein and related transcription factors

1 reference

12 December 2020

Differential immunohistochemical staining for DNA topoisomerase II alpha and beta in human tissues and for DNA topoisomerase II beta in non-Hodgkin's lymphomas

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKM434

1 reference

1475863

1475863

1 reference

1 reference

1 reference