Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells (Q24311397)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

Solute carrier family 25 member 33

2 February 2020

main subject

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regulation of reactive oxygen species biosynthetic process

GOA release 2020-03-11

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GOA release 2020-03-11

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1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Dmitri B. Papkovsky

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Rosemary O'Connor

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

C Favre

1

1 reference

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2 February 2020

M Leahy

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

10 May 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

29

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2 February 2020

page(s)

3964-3976

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

27

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Brick by brick: metabolism and tumor cell growth

2 February 2020

cites work

1 reference

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The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth

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Why do cancers have high aerobic glycolysis?

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TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein

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Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

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A simple salting out procedure for extracting DNA from human nucleated cells

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Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria.

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Akt stimulates aerobic glycolysis in cancer cells

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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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On the Origin of Cancer Cells

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PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response

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Mitochondrial mutations in cancer

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Mitochondrial signaling: the retrograde response

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Mitochondrial DNA mutations in human cancer

21 January 2018

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Inherited mitochondrial diseases of DNA replication

21 January 2018

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DNA replication and transcription in mammalian mitochondria

21 January 2018

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Redox-dependent signal transduction

21 January 2018

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Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

21 January 2018

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Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.

21 January 2018

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In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay

21 January 2018

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AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells

21 January 2018

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ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

21 January 2018

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Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.

21 January 2018

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Maintenance of mitochondrial DNA copy number and expression are essential for preservation of mitochondrial function and cell growth

21 January 2018

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Tumor suppressors and cell metabolism: a recipe for cancer growth

21 January 2018

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AMPK: a metabolic gauge regulating whole-body energy homeostasis

21 January 2018

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Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity, and cancer

21 January 2018

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Invasive potential induced under long-term oxidative stress in mammary epithelial cells

21 January 2018

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Progressive tumor features accompany epithelial-mesenchymal transition induced in mitochondrial DNA-depleted cells.

21 January 2018

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Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

21 January 2018

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Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1.

21 January 2018

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21 January 2018

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Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

21 January 2018

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Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.

21 January 2018

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21 January 2018

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Insulin-like growth factor-induced signals activate mitochondrial respiration

21 January 2018

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AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism

21 January 2018

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The signaling mechanism of ROS in tumor progression

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Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission.

21 January 2018

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Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)

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Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes

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Tumor Mitochondria and the Bioenergetics of Cancer Cells

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.146

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20453889%20AND%20SRC:MED&resulttype=core&format=json