Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B (Q24311684)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469807%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B (English)

1 reference

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7 January 2020

main subject

cell biology

0 references

Unc-5 netrin receptor B

1 reference

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Yue Feng

5

1 reference

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7 January 2020

Wen-Cheng Xiong

10

1 reference

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7 January 2020

author name string

Xiaoling Tang

1

1 reference

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7 January 2020

Sung-Wuk Jang

2

1 reference

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7 January 2020

Masashi Okada

3

1 reference

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7 January 2020

Chi-Bun Chan

4

1 reference

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7 January 2020

Yu Liu

6

1 reference

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7 January 2020

Shi-Wen Luo

7

1 reference

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7 January 2020

Yan Hong

8

1 reference

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7 January 2020

Nicolas Rama

9

1 reference

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7 January 2020

Patrick Mehlen

11

1 reference

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7 January 2020

Keqiang Ye

12

1 reference

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7 January 2020

language of work or name

English

0 references

publication date

11 May 2008

1 reference

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7 January 2020

1 reference

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7 January 2020

volume

10

1 reference

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7 January 2020

issue

6

1 reference

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7 January 2020

page(s)

698-706

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The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

7 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Focal adhesion kinase in netrin-1 signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

p53RDL1 regulates p53-dependent apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Pike tyrosine phosphorylation regulates its apoptotic cleavage during programmed cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Activation of FAK and Src are receptor-proximal events required for netrin signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Sperm membrane protein (hSMP-1) and RanBPM complex in the microtubule-organizing centre

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Surface expression of the netrin receptor UNC5H1 is regulated through a protein kinase C-interacting protein/protein kinase-dependent mechanism.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839190

DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18469807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18469807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB1732

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469807%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 January 2020

1050427490

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18469807%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

18469807

2 references