Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression (Q24312550)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0071906

TLE family member 5, transcriptional modulator

1 reference

TLE family member 2, transcriptional corepressor

1 reference

negative regulation of canonical Wnt signaling pathway

1 reference

Groucho Dmel_CG8384

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-9-159

author name string

Laura Arce

series ordinal

1

0 references

Kira T Pate

series ordinal

2

0 references

Marian L Waterman

series ordinal

3

0 references

language of work or name

English

0 references

publication date

2009

0 references

published in

BMC Cancer

0 references

volume

9

0 references

issue

1

0 references

page(s)

159

0 references

exact match

0 references

cites work

Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivo

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Six3 and Six6 activity is modulated by members of the groucho family

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All Tcf HMG box transcription factors interact with Groucho-related co-repressors

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Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

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Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats

19 March 2017

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The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

19 March 2017

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HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences

19 March 2017

1 reference

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Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

19 March 2017

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Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

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Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors

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A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development

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A role for Groucho tetramerization in transcriptional repression

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Wnt signaling inside the nucleus

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The 'Marx' of Groucho on development and disease

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An eh1-like motif in odd-skipped mediates recruitment of Groucho and repression in vivo

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HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription

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G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway

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27 September 2017

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Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription

27 September 2017

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27 September 2017

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The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

27 September 2017

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27 September 2017

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27 September 2017

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A conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos

27 September 2017

1 reference

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Tumour recurrence is associated with Jass grouping but not with differences in E-cadherin expression in moderately differentiated Dukes' B colorectal cancers.

27 September 2017

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27 September 2017

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27 September 2017

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Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

27 September 2017

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27 September 2017

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Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates.

27 September 2017

1 reference

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Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

30 May 2018

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Microsatellite instability in colorectal adenocarcinoma cell lines that have full-length adenomatous polyposis coli protein.

30 May 2018

1 reference

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Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

The APC tumour suppressor has a nuclear export function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-159

Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19460168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular Recognition of Transcriptional Repressor Motifs by the WD Domain of the Groucho/TLE Corepressor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19460168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-9-159

1 reference

Dimensions Publication ID

4475027

1006558139

0 references

Fatcat ID

release_bl7ile67tvetrmw3tw5qxi6z3u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bl7ile67tvetrmw3tw5qxi6z3u

mapped directly with Wikidata item

24 November 2022

based on heuristic

4475027

1 reference

1 reference

1 reference