A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein (Q24312803)

Transferrin

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Sorting nexin 33

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Beta-secretase 1

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Amyloid beta precursor protein

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positive regulation of membrane protein ectodomain proteolysis

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6

Elisabeth Kremmer

Elisabeth

Kremmer

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9 December 2023

9

Christian Haass

Christian

Haass

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9 December 2023

Peer-Hendrik Kuhn

5

Peer-Hendrik

Kuhn

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9 December 2023

Stefan F Lichtenthaler

10

object named as

Stefan F Lichtenthaler

Stefan F

Lichtenthaler

1 reference

9 December 2023

Susanne Schöbel

1

Susanne

Schöbel

1 reference

9 December 2023

Stephanie Neumann

2

Stephanie

Neumann

1 reference

9 December 2023

Maren Hertweck

3

Maren

Hertweck

1 reference

9 December 2023

Bastian Dislich

4

Bastian

Dislich

1 reference

9 December 2023

Brian Seed

7

Brian

Seed

1 reference

9 December 2023

Ralf Baumeister

8

Ralf

Baumeister

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Journal of Biological Chemistry

9 December 2023

language of work or name

English

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publication date

23 May 2008

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published in

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volume

283

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issue

21

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page(s)

14257-68

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cites work

ADAMs family members as amyloid precursor protein alpha-secretases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

The Phox (PX) domain proteins and membrane traffic

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Expression cloning screen for modifiers of amyloid precursor protein shedding

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Bar domain proteins: a role in tubulation, scission and actin assembly in clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Shedding light on ADAM metalloproteinases

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Beta-secretase inhibition for the treatment of Alzheimer's disease--promise and challenge

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Mutations in the transmembrane domain of APP altering gamma-secretase specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Rab proteins as membrane organizers

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease

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https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Pathways of clathrin-independent endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Sorting out the cellular functions of sorting nexins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

A large family of endosome-localized proteins related to sorting nexin 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Dimerization is required for SH3PX1 tyrosine phosphorylation in response to epidermal growth factor signalling and interaction with ACK2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Beta-amyloid precursor protein cleavage by a membrane-bound protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Inhibition of Receptor-mediated Endocytosis Demonstrates Generation of Amyloid β-Protein at the Cell Surface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Regulated membrane recruitment of dynamin-2 mediated by sorting nexin 9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Effects of mutant rat dynamin on endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

L-selectin: mechanisms and physiological significance of ectodomain cleavage.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Sorting nexins--unifying trends and new perspectives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

An essential role for ectodomain shedding in mammalian development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Dynamin and its role in membrane fission

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Ectodomain shedding of the amyloid precursor protein: cellular control mechanisms and novel modifiers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Two novel mutations in dynamin-2 cause axonal Charcot-Marie-Tooth disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801531200

7 January 2021

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Identifiers

DOI

10.1074/JBC.M801531200

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Fatcat ID

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