Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation (Q24316156)

epidermal growth factor

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Interleukin 2 receptor subunit beta

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negative regulation of apoptotic process

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Interleukin 3

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author name string

T Miyazaki

1

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Z J Liu

2

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A Kawahara

3

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Y Minami

4

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K Yamada

5

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Y Tsujimoto

6

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E L Barsoumian

7

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R M Permutter

8

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T Taniguchi

Human interleukin 2 (IL 2) receptor beta chain allows transduction of IL 2-induced proliferation signal(s) in a murine cell line

9

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language of work or name

English

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publication date

21 April 1995

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published in

Cell

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volume

81

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issue

2

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page(s)

223-31

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cites work

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

The IL-2/IL-2 receptor system: a current overview

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Bcl-2: a repressor of lymphocyte death

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Programmed cell death, apoptosis and killer genes

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Oncogenes and cell death

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

The control of apoptosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signalling

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

The multi-subunit interleukin-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2F0092-8674%2895%2990332-1

7 January 2021