The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability (Q24317171)

regulation of attachment of spindle microtubules to kinetochore

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

J Du

1

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X Cai

2

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J Yao

3

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X Ding

4

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Q Wu

5

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S Pei

6

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K Jiang

7

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Y Zhang

8

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W Wang

9

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Y Shi

10

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Y Lai

11

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J Shen

12

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M Teng

13

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H Huang

14

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Q Fei

15

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E S Reddy

16

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J Zhu

17

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C Jin

18

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X Yao

Tension, microtubule rearrangements, and the proper distribution of chromosomes in mitosis.

19

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language of work or name

English

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publication date

3 July 2008

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published in

Oncogene

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volume

27

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page(s)

4107-14

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issue

29

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cites work

1 reference

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Centrosome and kinetochore movement during mitosis

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The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

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Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation

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Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore

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The Ndc80 complex: hub of kinetochore activity

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Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1.

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Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites

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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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Centromere cohesion: regulating the guardian

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The Nek2 protein kinase: a novel regulator of centrosome structure

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Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

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Nek2 kinase in chromosome instability and cancer

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Function and regulation of Aurora/Ipl1p kinase family in cell division

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The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments

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Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment

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NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling

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The spindle-assembly checkpoint in space and time

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Microtubules, chromosome movement, and reorientation after chromosomes are detached from the spindle by micromanipulation

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Mitotic kinases as regulators of cell division and its checkpoints

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Genome-wide genetic analysis of polyploidy in yeast

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CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

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