Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner (Q24321591)

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6 January 2020

title

Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner (English)

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6 January 2020

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vascular endothelial growth factor A

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regulation of nitric oxide mediated signal transduction

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Thrombospondin-1

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Vascular endothelial growth factor A

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Phosphodiesterase 2A, cGMP-stimulated

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Phosphodiesterase 5A, cGMP-specific

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author

David D Roberts

6

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6 January 2020

author name string

Jeff S Isenberg

1

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6 January 2020

Lisa A Ridnour

2

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6 January 2020

Elizabeth M Perruccio

3

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6 January 2020

Michael G Espey

4

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6 January 2020

David A Wink

5

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6 January 2020

language of work or name

English

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publication date

6 September 2005

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Proceedings of the National Academy of Sciences of the United States of America

6 January 2020

published in

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6 January 2020

volume

102

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6 January 2020

page(s)

13141-13146

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6 January 2020

issue

37

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Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I

6 January 2020

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1 reference

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

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Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

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27 September 2017

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27 September 2017

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Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2.

27 September 2017

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Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide.

27 September 2017

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27 September 2017

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Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

27 September 2017

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Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis

27 September 2017

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Thrombospondins 1 and 2 function as inhibitors of angiogenesis

27 September 2017

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27 September 2017

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Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?

27 September 2017

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Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway

27 September 2017

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Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability

27 September 2017

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A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.

27 September 2017

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Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia

27 September 2017

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27 September 2017

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Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1.

27 September 2017

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CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells

27 September 2017

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Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

27 September 2017

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27 September 2017

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29 November 2018

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29 November 2018

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Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells

29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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12 December 2020

Redox regulation of vascular angiogenesis

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12 December 2020

Angiosuppressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin

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12 December 2020

Alpha4beta1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo

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12 December 2020

Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin

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12 December 2020

Neutrophil thrombospondin receptors are linked to GTP-binding proteins

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12 December 2020

Cyclic GMP-dependent protein kinase is required for thrombospondin and tenascin mediated focal adhesion disassembly

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12 December 2020

Cyclic GMP-dependent protein kinase inhibits osteopontin and thrombospondin production in rat aortic smooth muscle cells

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12 December 2020

Plasma thrombospondin levels in patients with colorectal carcinoma

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12 December 2020

Suppression of hepatoma growth and angiogenesis by a fumagillin derivative TNP470: possible involvement of nitric oxide synthase

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12 December 2020

Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells

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12 December 2020

Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells

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12 December 2020

Nitric oxide inhibits proliferation of human endothelial cells via a mechanism independent of cGMP

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0502977102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16150726%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

0 references

1 reference

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6 January 2020

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