Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway (Q24328745)

regulation of I-kappaB kinase/NF-kappaB signaling

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

8

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author name string

Antoine Tinel

1

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Sophie Janssens

2

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Saskia Lippens

3

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Solange Cuenin

4

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Emmanuelle Logette

5

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Bastienne Jaccard

6

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Manfredo Quadroni

Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage

7

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language of work or name

English

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publication date

10 January 2007

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published in

The EMBO Journal

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volume

26

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issue

1

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page(s)

197-208

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cites work

1 reference

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

19 March 2017

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Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

19 March 2017

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Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

19 March 2017

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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

19 March 2017

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LRDD, a novel leucine rich repeat and death domain containing protein

19 March 2017

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A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96

19 March 2017

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The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

19 March 2017

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Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif

19 March 2017

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Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

19 March 2017

1 reference

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Caspase-2 function in response to DNA damage

19 March 2017

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Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif

19 March 2017

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WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

19 March 2017

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

19 March 2017

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alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor

19 March 2017

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A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

19 March 2017

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The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development

19 March 2017

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ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily

19 March 2017

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Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

19 March 2017

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Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

19 March 2017

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PIDD mediates NF-kappaB activation in response to DNA damage

27 September 2017

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Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase

27 September 2017

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Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

27 September 2017

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Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif

27 September 2017

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The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

27 September 2017

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A novel Apaf-1-independent putative caspase-2 activation complex

27 September 2017

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Protein splicing and its applications

27 September 2017

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Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

27 September 2017

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Protein splicing and related forms of protein autoprocessing

27 September 2017

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Autoproteolysis in nucleoporin biogenesis

27 September 2017

1 reference

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p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury

27 September 2017

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

29 November 2018

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Toward a Clinical Molecular Scanner for Proteome Research: Parallel Protein Chemical Processing before and during Western Blot

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17159900

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17159900

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601473

1 reference

1 reference

1 reference

PubMed publication ID

17159900

1 reference