The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling (Q24336423)

Enhancer of zeste 2 polycomb repressive complex 2 subunit

GOA release 2020-03-11

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negative regulation of retinoic acid receptor signaling pathway

GOA release 2020-03-11

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GOA release 2020-03-11

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René Bernards

6

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author name string

Mirjam T Epping

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Liming Wang

2

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Michael J Edel

3

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Leone Carlée

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Maria Hernandez

Retinoic acid receptor and retinoid X receptor expression in retinoic acid-resistant human tumor cell lines

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language of work or name

English

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publication date

23 September 2005

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published in

Cell

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volume

122

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issue

6

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page(s)

835-47

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cites work

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Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

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The promise of retinoids to fight against cancer.

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

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The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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The polycomb group protein EZH2 is involved in progression of prostate cancer

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Comparison of medulloblastoma and normal neural transcriptomes identifies a restricted set of activated genes

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PRAME, a gene encoding an antigen recognized on a human melanoma by cytolytic T cells, is expressed in acute leukaemia cells

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Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

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Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

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The tumor-associated antigen PRAME is universally expressed in high-stage neuroblastoma and associated with poor outcome

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