Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS (Q24336425)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Furqan Sami

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Nina Rajpurohit

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Iris Lindberg

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

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publication date

1 November 2013

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published in

FEBS Letters

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

587

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13 June 2020

issue

21

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13 June 2020

page(s)

3406-3411

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

13 June 2020

cites work

1 reference

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Neuroendocrine secretory protein 7B2: structure, expression and functions

19 March 2017

1 reference

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7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

19 March 2017

1 reference

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The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins

19 March 2017

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The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site

19 March 2017

1 reference

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Embryonic gene expression and pro-protein processing of proSAAS during rodent development

19 March 2017

1 reference

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Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells

19 March 2017

1 reference

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Amylin deposition in the brain: A second amyloid in Alzheimer disease?

19 March 2017

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Improved characterization of the insulin secretory granule proteomes

27 September 2017

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Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets

27 September 2017

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Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline.

27 September 2017

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Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

27 September 2017

1 reference

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The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors

27 September 2017

1 reference

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The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

27 September 2017

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Common features between diabetes mellitus and Alzheimer's disease

27 September 2017

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Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol.

27 September 2017

1 reference

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The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

27 September 2017

1 reference

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Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

27 September 2017

1 reference

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An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene Expression (SAGE).

27 September 2017

1 reference

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Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845801

Functional characterization of ProSAAS: similarities and differences with 7B2.

27 September 2017

1 reference

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Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1.

27 September 2017

1 reference

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Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

27 September 2017

1 reference

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The cell biology of the prohormone convertases PC1 and PC2.

27 September 2017

1 reference

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A 36-residue peptide contains all of the information required for 7B2-mediated activation of prohormone convertase 2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845801

Involvement of a polyproline helix-like structure in the interaction of 7B2 with prohormone convertase 2.

27 September 2017

1 reference

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Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

27 September 2017

1 reference

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Amyloid fibril toxicity in Alzheimer's disease and diabetes

27 September 2017

1 reference

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The neuroendocrine protein 7B2 acts as a molecular chaperone in the in vitro folding of human insulin-like growth factor-1 secreted from yeast

27 September 2017

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The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

27 September 2017

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Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

30 May 2018

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Crossref

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.09.006

Androgen deprivation by activating the liver X receptor

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.09.006

pGenTHREADER and pDomTHREADER: new methods for improved protein fold recognition and superfamily discrimination

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2013.09.006

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

21 January 2018

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12 December 2020

Pro islet amyloid polypeptide (ProIAPP) immunoreactivity in the islets of Langerhans

1 reference

12 December 2020

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

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12 December 2020

Neurotoxicity of human amylin in rat primary hippocampal cultures: similarity to Alzheimer's disease amyloid-beta neurotoxicity

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12 December 2020

Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

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12 December 2020

Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice

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12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

12 December 2020

Prohormone convertases 1/3, 2, furin and protein 7B2 (Secretogranin V) in endocrine cells of the human pancreas

1 reference

12 December 2020

7B2 prevents unfolding and aggregation of prohormone convertase 2

1 reference

12 December 2020

Proinsulin maturation disorder is a contributor to the defect of subsequent conversion to insulin in β-cells

1 reference

12 December 2020

10.1016/J.FEBSLET.2013.09.006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24042052%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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13 June 2020

1 reference

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