Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1 (Q24337154)

Nucleotide binding oligomerization domain containing 2

1 reference

receptor interacting serine/threonine kinase 2

1 reference

cellular response to muramyl dipeptide

1 reference

Receptor (TNFRSF)-interacting serine-threonine kinase 2

1 reference

9

Ramnik Xavier

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author name string

Yun Zhao

1

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Carmen Alonso

2

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Isabel Ballester

3

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Joo Hye Song

4

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Sun Young Chang

5

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Bayasi Guleng

6

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Seiji Arihiro

7

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Peter J Murray

8

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Koichi S Kobayashi

10

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Hans-Christian Reinecker

Inflammatory Bowel Diseases

11

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language of work or name

English

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publication date

April 2012

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published in

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volume

18

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issue

4

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page(s)

603-12

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cites work

GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors

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The selectivity of protein kinase inhibitors: a further update

19 March 2017

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

19 March 2017

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Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

19 March 2017

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RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

19 March 2017

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

19 March 2017

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Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

19 March 2017

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RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

19 March 2017

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

19 March 2017

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

19 March 2017

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Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

19 March 2017

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RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis

19 March 2017

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

19 March 2017

1 reference

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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

19 March 2017

1 reference

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Unravelling the pathogenesis of inflammatory bowel disease

19 March 2017

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Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.

7 April 2017

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Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

27 September 2017

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Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila

27 September 2017

1 reference

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Large-scale proteomics analysis of the human kinome

27 September 2017

1 reference

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The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection

27 September 2017

1 reference

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Tyrosine kinases and inflammatory signalling

27 September 2017

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Phagocytosis and comparative innate immunity: learning on the fly.

27 September 2017

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AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling

27 September 2017

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NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

27 September 2017

1 reference

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The RIP kinases: crucial integrators of cellular stress

27 September 2017

1 reference

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Role of vav1- and src-related tyrosine kinases in macrophage activation by CpG DNA.

27 September 2017

1 reference

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CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594873

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

27 September 2017

1 reference

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CARD15 mutations in Blau syndrome

27 September 2017

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The src family-selective tyrosine kinase inhibitor PP1 blocks LPS and IFN-gamma-mediated TNF and iNOS production in murine macrophages.

27 September 2017

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Innate signals from Nod2 block respiratory tolerance and program TH2-driven allergic inflammation

27 September 2017

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NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

30 May 2018

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Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594873

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594873

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

30 May 2018

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Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.

21 January 2018

1 reference

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease

21 January 2018

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TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T-cell activation

21 January 2018

1 reference

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

21 January 2018

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Mucosal NOD2 expression and NF-κB activation in pediatric Crohnʼs disease

21 January 2018

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Cellular targets of gefitinib

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594873

Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21887730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21887730