Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo (Q24338802)

positive regulation of dendritic spine development

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

4

Fred Van Leuven

0 references

Jochen Herms

5

object named as

Jochen Herms

0 references

author name string

Christian K E Jung

1

0 references

Martin Fuhrmann

2

0 references

Kamran Honarnejad

Journal of Neurochemistry

3

0 references

language of work or name

English

0 references

publication date

December 2011

0 references

published in

0 references

volume

119

0 references

issue

5

0 references

page(s)

1064-73

0 references

cites work

Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Early-onset Alzheimer disease in an Italian family with presenilin-1 double mutation E318G and G394V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Dendritic pathology in prion disease starts at the synaptic spine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Staining protocol for organotypic hippocampal slice cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

In vivo dendritic calcium dynamics in deep-layer cortical pyramidal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Calcium dynamics of spines depend on their dendritic location

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Transient and persistent dendritic spines in the neocortex in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Spine growth precedes synapse formation in the adult neocortex in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Effects of N-cadherin disruption on spine morphological dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Amyloid-independent mechanisms in Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

FAD mutations in amyloid precursor protein do not directly perturb intracellular calcium homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Distribution of the calcium-binding proteins parvalbumin and calbindin-D28k in the sensorimotor cortex of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Role of presenilins in neuronal calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

Identification of presenilin 1-selective γ-secretase inhibitors with reconstituted γ-secretase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

7 January 2021

Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

7 January 2021

Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

7 January 2021

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07503.X

7 January 2021