The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels (Q24339599)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels (English)

1 reference

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Atonal bHLH transcription factor 8

1 March 2020

main subject

1 reference

GOA release 2020-03-11

E-box binding

1 reference

GOA release 2020-03-11

author

Joe Varghese

2

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1 March 2020

Robert J. Simpson

6

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1 March 2020

author name string

Neeta Patel

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Patarabutr Masaratana

3

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1 March 2020

Gladys O Latunde-Dada

4

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1 March 2020

Molly Jacob

5

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1 March 2020

Andrew T McKie

7

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1 March 2020

language of work or name

English

0 references

publication date

16 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Haematology

1 March 2020

published in

1 reference

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1 March 2020

volume

164

1 reference

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1 March 2020

issue

4

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1 March 2020

page(s)

586-596

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Interleukin-6 induces hepcidin expression through STAT3

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Regulation of transferrin receptor 2 protein levels by transferrin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Differential interactions of Id proteins with basic-helix-loop-helix transcription factors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Cis and trans regulation of hepcidin expression by upstream stimulatory factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Suppression of hepcidin during anemia requires erythropoietic activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Animal models with enhanced erythropoiesis and iron absorption

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Math6, a bHLH gene expressed in the developing nervous system, regulates neuronal versus glial differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Identification of a novel transcriptional activity of mammalian Id proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Binding of myc proteins to canonical and noncanonical DNA sequences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Regulators of iron balance in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Iron metabolism in the hemoglobin-deficit mouse: correlation of diferric transferrin with hepcidin expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Iron absorption by hypotransferrinaemic mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232863

Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.

30 May 2018

1 reference

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

21 January 2018

1 reference

Transferrin therapy ameliorates disease in beta-thalassemic mice

21 January 2018

1 reference

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

21 January 2018

1 reference

Regulation of hepcidin expression at high altitude

21 January 2018

1 reference

In vivo studies on the relationship between intestinal iron (Fe3+) absorption, hypoxia and erythropoiesis in the mouse

21 January 2018

1 reference

12 December 2020

Effect of exchange transfusion of reticulocytes on in vitro and in vivo intestinal iron (Fe3+) absorption in mice

1 reference

12 December 2020

Hepcidin and iron-loading anemias

1 reference

12 December 2020

Iron absorption in hepcidin1 knockout mice

1 reference

12 December 2020

Iron metabolism in hepcidin1 knockout mice in response to phenylhydrazine-induced hemolysis

1 reference

12 December 2020

Identifiers

DOI

10.1111/BJH.12649

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24236640

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24236640%20AND%20SRC:MED&resulttype=core&format=json