Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice (Q34783878)

4 August 2017

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice (English)

1 reference

4 August 2017

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Léon Kautz

2

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Tomas Ganz

object named as

Tomas Ganz

9

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author name string

Emilio Ramos

1

1 reference

4 August 2017

Richard Rodriguez

3

1 reference

4 August 2017

Michael Hansen

4

1 reference

4 August 2017

Victoria Gabayan

5

1 reference

4 August 2017

Yelena Ginzburg

6

1 reference

4 August 2017

Marie-Paule Roth

7

1 reference

4 August 2017

Elizabeta Nemeth

8

1 reference

4 August 2017

language of work or name

English

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publication date

1 April 2011

1 reference

4 August 2017

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4 August 2017

53

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4 August 2017

4

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4 August 2017

1333-1341

1 reference

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Hfe acts in hepatocytes to prevent hemochromatosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

In vivo imaging of hepcidin promoter stimulation by iron and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Suppression of hepcidin during anemia requires erythropoietic activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Mechanisms of iron accumulation in hereditary hemochromatosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Immunoassay for human serum hepcidin

7 July 2018

1 reference

Transferrin therapy ameliorates disease in beta-thalassemic mice.

21 January 2018

1 reference

Food intake, water intake, and drinking spout side preference of 28 mouse strains

21 January 2018

1 reference

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

21 January 2018

1 reference

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

21 January 2018

1 reference

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

21 January 2018

1 reference

Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia

21 January 2018

1 reference

Hepatic expression of hemochromatosis genes in two mouse strains after phlebotomy and iron overload.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074982

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21480335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.24178

1 reference

4 August 2017

1 reference

4 August 2017

1 reference