Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development (Q24529871)

4 July 2017

title

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development (English)

1 reference

4 July 2017

0 references

Miao-Hsueh Chen

1

1 reference

4 July 2017

Nan Gao

series ordinal

2

1 reference

4 July 2017

Takatoshi Kawakami

series ordinal

3

1 reference

4 July 2017

Pao-Tien Chuang

series ordinal

4

1 reference

4 July 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

Molecular and Cellular Biology

4 July 2017

published in

1 reference

4 July 2017

volume

25

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4 July 2017

issue

16

1 reference

4 July 2017

page(s)

7042-7053

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Suppressor of fused regulates Gli activity through a dual binding mechanism

4 July 2017

cites work

1 reference

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24 March 2017

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Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.

24 March 2017

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Gli regulation by the opposing activities of fused and suppressor of fused

24 March 2017

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

24 March 2017

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Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

24 March 2017

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Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

24 March 2017

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Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

24 March 2017

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

24 March 2017

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

24 March 2017

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The GLI-Kruppel family of human genes

24 March 2017

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Lipoprotein particles are required for Hedgehog and Wingless signalling

24 March 2017

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Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord

24 March 2017

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The Hedgehog response network: sensors, switches, and routers

24 March 2017

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FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues

24 March 2017

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Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

24 March 2017

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All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3

24 March 2017

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Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

24 March 2017

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Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction

24 March 2017

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Characterization of the physical interaction of Gli proteins with SUFU proteins

24 March 2017

1 reference

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Patched acts catalytically to suppress the activity of Smoothened

24 March 2017

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Gli1 can rescue the in vivo function of Gli2

24 March 2017

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Hedgehog signaling in animal development: paradigms and principles

24 March 2017

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Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

24 March 2017

1 reference

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The Hedgehog and Wnt signalling pathways in cancer

24 March 2017

1 reference

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The Suppressor of fused gene, involved in Hedgehog signal transduction in Drosophila, is conserved in mammals

24 March 2017

1 reference

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Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

24 March 2017

1 reference

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Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

24 March 2017

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Gli proteins encode context-dependent positive and negative functions: implications for development and disease

24 March 2017

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Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

24 March 2017

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Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system

24 March 2017

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Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

24 March 2017

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A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

24 March 2017

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gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development

24 March 2017

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Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

24 March 2017

1 reference

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Mutations affecting segment number and polarity in Drosophila

24 March 2017

1 reference

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Identification of an amplified, highly expressed gene in a human glioma

24 March 2017

1 reference

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Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Hedgehog signalling in the mouse requires intraflagellar transport proteins

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

24 March 2017

1 reference

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Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice

24 March 2017

1 reference

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Developmental roles and clinical significance of hedgehog signaling

24 March 2017

1 reference

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Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

7 April 2017

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Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

7 April 2017

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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

7 April 2017

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HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

7 April 2017

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Communicating with Hedgehogs

7 April 2017

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Characterization of KIF7 gene in silico.

27 September 2017

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An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling

27 September 2017

1 reference

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Novel lipid modifications of secreted protein signals

27 September 2017

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27 September 2017

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Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

27 September 2017

1 reference

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Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog

27 September 2017

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Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

27 September 2017

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Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused

27 September 2017

1 reference

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The sterol-sensing domain: multiple families, a unique role?

27 September 2017

1 reference

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The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling

27 September 2017

1 reference

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The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells

27 September 2017

1 reference

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Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus

27 September 2017

1 reference

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Biochemical evidence that patched is the Hedgehog receptor

27 September 2017

1 reference

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Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila

27 September 2017

1 reference

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Phosphorylation of the fused protein kinase in response to signaling from hedgehog

27 September 2017

1 reference

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Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

27 September 2017

1 reference

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The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment

27 September 2017

1 reference

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Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster

27 September 2017

1 reference

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Expression of the human FUSED protein in Drosophila

27 September 2017

1 reference

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KIF27 is one of orthologs for Drosophila Costal-2.

30 May 2018

1 reference

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Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.

30 May 2018

1 reference

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Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators

30 May 2018

1 reference

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Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway

30 May 2018

1 reference

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Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

30 May 2018

1 reference

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smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

30 May 2018

1 reference

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The GLI gene is a member of the Kruppel family of zinc finger proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

30 May 2018

1 reference

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Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Genetic evidence that Sil is required for the Sonic Hedgehog response pathway.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Genetic dissection of the Drosophila Cubitus interruptus signaling complex

29 November 2018

1 reference

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Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Identification of a tetrameric hedgehog signaling complex

29 November 2018

1 reference

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Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.

29 November 2018

1 reference

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Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Modulation of Hedgehog target gene expression by the Fused serine-threonine kinase in wing imaginal discs.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Analysis of Fgf8 gene function in vertebrate development

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190231

Genetic analysis of hedgehog signalling in the Drosophila embryo

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16055716

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.16.7042-7053.2005

1 reference

OpenCitations bibliographic resource ID

4 July 2017

1505825

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

4 July 2017

1 reference