PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating Akt (Q24564005)

2

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Todd G Kroll

3

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Paulette Allard

4

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Keqiang Ye

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

4 May 2004

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published in

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volume

101

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issue

18

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page(s)

6993-8

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cites work

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

24 March 2017

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Direct control of the Forkhead transcription factor AFX by protein kinase B

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Lamin proteolysis facilitates nuclear events during apoptosis

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

24 March 2017

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

24 March 2017

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PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

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Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

24 March 2017

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CREB is a regulatory target for the protein kinase Akt/PKB

24 March 2017

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Regulation of cell death protease caspase-9 by phosphorylation

24 March 2017

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

24 March 2017

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

24 March 2017

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Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1

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The protein kinase B/Akt signalling pathway in human malignancy

24 March 2017

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PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

24 March 2017

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

7 April 2017

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Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

7 April 2017

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Inhibition of protein kinase B/Akt. implications for cancer therapy

27 September 2017

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Molecular rearrangements and morphology in thyroid cancer

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27 September 2017

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27 September 2017

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Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase

27 September 2017

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Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells

27 September 2017

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

27 September 2017

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Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0400921101

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0400921101

The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.

21 January 2018

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Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/15118108

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0400921101

1 reference

3694142

ADS bibcode

2004PNAS..101.6993A

0 references

3694142

1 reference

1 reference

1 reference