Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells (Q24607826)

10

object named as

Walter Schulz-Schaeffer

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author name string

Ella L Kim

1

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Robin Wüstenberg

2

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Anne Rübsam

3

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Christoph Schmitz-Salue

4

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Gabriele Warnecke

5

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Eva-Maria Bücker

6

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Nadine Pettkus

7

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Daniel Speidel

8

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Wolfgang Deppert

11

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Alf Giese

Inhibition of macroautophagy triggers apoptosis

12

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language of work or name

English

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publication date

April 2010

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published in

Neuro-Oncology

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volume

12

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issue

4

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page(s)

389-400

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cites work

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Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis

27 September 2017

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Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.

27 September 2017

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27 September 2017

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Coping with stress: multiple ways to activate p53.

27 September 2017

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Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.

27 September 2017

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Structure-function correlation of chloroquine and analogues as transgene expression enhancers in nonviral gene delivery

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors

27 September 2017

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27 September 2017

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27 September 2017

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Comparative assessment of the functional p53 status in glioma cells.

27 September 2017

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Therapy of glioblastoma multiforme improved by the antimutagenic chloroquine

27 September 2017

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P53 and prognosis: new insights and further complexity

27 September 2017

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Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons

30 May 2018

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Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

30 May 2018

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Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent

30 May 2018

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30 May 2018

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30 May 2018

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Risks and benefits of chloroquine use in anticancer strategies.

28 November 2018

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Inactivation of p53 sensitizes astrocytic glioma cells to BCNU and temozolomide, but not cisplatin

28 November 2018

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Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide

28 November 2018

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Genetic pathways to glioblastoma: a population-based study

28 November 2018

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28 November 2018

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Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results

28 November 2018

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28 November 2018

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Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand.

28 November 2018

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Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea

28 November 2018

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Mitochondrial depolarization is not required for neuronal apoptosis.

28 November 2018

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Apoptosis in gliomas: molecular mechanisms and therapeutic implications

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