Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism (Q24608263)

21 June 2017

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism (English)

1 reference

21 June 2017

0 references

1 reference

7

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21 June 2017

Anil Kumar

1

1 reference

21 June 2017

John C Lawrence

2

1 reference

21 June 2017

Dae Young Jung

3

1 reference

21 June 2017

Hwi Jin Ko

4

1 reference

21 June 2017

Susanna R Keller

5

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21 June 2017

Jason K Kim

6

1 reference

21 June 2017

Thurl E Harris

8

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21 June 2017

language of work or name

English

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publication date

23 March 2010

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21 June 2017

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21 June 2017

59

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21 June 2017

1397-1406

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21 June 2017

6

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

21 June 2017

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2

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mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

7 April 2017

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Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

7 April 2017

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

7 April 2017

1 reference

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

7 April 2017

1 reference

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Mechanism of activation of protein kinase B by insulin and IGF-1

7 April 2017

1 reference

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TOR signaling in growth and metabolism

7 April 2017

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Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane

7 April 2017

1 reference

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

7 April 2017

1 reference

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

7 April 2017

1 reference

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Upstream and downstream of mTOR

7 April 2017

1 reference

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Molecular mechanisms regulating hormone-sensitive lipase and lipolysis

7 April 2017

1 reference

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The insulin-regulated aminopeptidase: a companion and regulator of GLUT4

7 April 2017

1 reference

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Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

7 April 2017

1 reference

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

7 April 2017

1 reference

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Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

7 April 2017

1 reference

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Adipose tissue as an endocrine organ

7 April 2017

1 reference

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A central role for JNK in obesity and insulin resistance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Cellular mechanisms of insulin resistance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

mTOR complex 2 in adipose tissue negatively controls whole-body growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

The GLUT4 glucose transporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Regulation of lipolysis in adipocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

27 September 2017

1 reference

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Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Etiology of insulin resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Insulin resistance due to phosphorylation of insulin receptor substrate-1 at serine 302.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines

27 September 2017

1 reference

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Hormone-sensitive lipase--new roles for an old enzyme

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Role of Akt/protein kinase B in metabolism.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overview

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874700

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

28 November 2018

1 reference

12 December 2020

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

12 December 2020

Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance--is insulin resistance initiated in the adipose tissue?

1 reference

12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB09-1061

1 reference

OpenCitations bibliographic resource ID

21 June 2017

0 references

2007122

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference