Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia (Q24627258)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14718672%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia (English)

1 reference

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17 November 2019

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acute myeloid leukemia

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6

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17 November 2019

Stefan Bohlander

7

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17 November 2019

4

Wolfgang Hiddemann

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17 November 2019

Michaela Feuring-Buske

8

object named as

Michaela Feuring-Buske

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17 November 2019

2

Monica Cusan

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17 November 2019

author name string

Vijay P S Rawat

1

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17 November 2019

Aniruddha Deshpande

3

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17 November 2019

Christian Buske

9

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17 November 2019

Leticia Quintanilla-Martinez

5

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17 November 2019

language of work or name

English

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publication date

12 January 2004

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17 November 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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17 November 2019

volume

101

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17 November 2019

issue

3

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17 November 2019

page(s)

817-822

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PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins

17 November 2019

cites work

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Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation

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Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

7 April 2017

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7 April 2017

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The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo

27 September 2017

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Identification of new translocations involving ETV6 in hematologic malignancies by fluorescence in situ hybridization and spectral karyotyping

27 September 2017

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Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.

27 September 2017

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Fusion genes in leukemia: an emerging network

27 September 2017

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Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia

27 September 2017

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Homeobox genes in leukemogenesis

27 September 2017

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The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

27 September 2017

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Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

27 September 2017

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The role of chromosome translocations in leukemogenesis.

27 September 2017

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Transducing positional information to the Hox genes: critical interaction of cdx gene products with position-sensitive regulatory elements.

27 September 2017

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Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

27 September 2017

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

27 September 2017

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27 September 2017

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27 September 2017

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Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

27 September 2017

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Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific

27 September 2017

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Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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The Tel-Abl (ETV6-Abl) tyrosine kinase, product of complex (9;12) translocations in human leukemia, induces distinct myeloproliferative disease in mice

30 May 2018

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A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene.

21 January 2018

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Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice.

21 January 2018

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Genome‐wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation‐mediated fusion events

21 January 2018

1 reference

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Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

21 January 2018

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Fusion of ETV6 to the caudal-related homeobox gene CDX2 in acute myeloid leukemia with the t(12;13)(p13;q12).

21 January 2018

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Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

28 November 2018

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12 December 2020

A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors

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12 December 2020

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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12 December 2020

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

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12 December 2020

Expression profile of wild-type ETV6 in childhood acute leukaemia

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12 December 2020

Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in myeloproliferative disorders.

1 reference

12 December 2020

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0305555101

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14718672%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

0 references

1 reference

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17 November 2019

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