ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 (Q24647310)

1

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Julie Birraux

2

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Leopoldine Tchouandong

3

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Olivia Barton

4

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Atsushi Shibata

5

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Sandro Conrad

6

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Aaron A Goodarzi

7

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Andrea Krempler

8

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Penny A Jeggo

9

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Markus Löbrich

CDK targets Sae2 to control DNA-end resection and homologous recombination

10

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language of work or name

English

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publication date

4 November 2009

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published in

The EMBO Journal

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volume

28

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issue

21

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page(s)

3413-27

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cites work

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Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

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DNA-PK autophosphorylation facilitates Artemis endonuclease activity

7 April 2017

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A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

7 April 2017

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In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair

7 April 2017

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Non-homologous end-joining, a sticky affair

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

7 April 2017

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Molecular views of recombination proteins and their control

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Pathways of DNA double-strand break repair during the mammalian cell cycle

7 April 2017

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

7 April 2017

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Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation

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Biallelic inactivation of BRCA2 in Fanconi anemia

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BRCA2 is required for homology-directed repair of chromosomal breaks

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Brca1 controls homology-directed DNA repair

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The impact of heterochromatin on DSB repair

7 April 2017

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ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

27 September 2017

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Differential regulation of the cellular response to DNA double-strand breaks in G1.

27 September 2017

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Mus81 is essential for sister chromatid recombination at broken replication forks

27 September 2017

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Quality control of DNA break metabolism: in the 'end', it's a good thing

27 September 2017

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The endless tale of non-homologous end-joining

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Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.

27 September 2017

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V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.

27 September 2017

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BRCA2: a universal recombinase regulator.

27 September 2017

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Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle.

27 September 2017

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DNA double-strand break repair: all's well that ends well

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Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

27 September 2017

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ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks

27 September 2017

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27 September 2017

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ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining

27 September 2017

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Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells

27 September 2017

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A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

27 September 2017

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Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM(-/-) and c-Abl(-/-) cells

27 September 2017

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DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination

27 September 2017

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Detection of repair activity during the DNA damage-induced G2 delay in human cancer cells

27 September 2017

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Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells

27 September 2017

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The controlling role of ATM in homologous recombinational repair of DNA damage

27 September 2017

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Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

27 September 2017

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Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells

27 September 2017

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Repair of x-ray-induced DNA double-strand breaks in specific Not I restriction fragments in human fibroblasts: joining of correct and incorrect ends

27 September 2017

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DNA-PKcs and ATM co-regulate DNA double-strand break repair

27 September 2017

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Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

30 May 2018

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The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

30 May 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2009.276

Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells.

21 January 2018

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The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

21 January 2018

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Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches

21 January 2018

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Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression

21 January 2018

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From DNA end chemistry to cell-cycle response: the importance of structure, even when it's broken.

21 January 2018

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A method for detecting sister chromatid exchanges using prematurely condensed chromosomes and immunogold-silver staining

21 January 2018

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12 December 2020

BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo

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12 December 2020

A backup DNA repair pathway moves to the forefront

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12 December 2020

X-irradiation of cells on glass slides has a dose doubling impact

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12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.276

1 reference

1706152

1706152

1 reference

1 reference

1 reference