Macrophages promote axon regeneration with concurrent neurotoxicity (Q24648617)

1

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Satoshi Nakamura

2

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Zhen Guan

3

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Daniel P Ankeny

5

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Phillip G Popovich

Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons

6

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language of work or name

English

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publication date

25 March 2009

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published in

Journal of Neuroscience

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volume

29

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issue

12

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page(s)

3956-68

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cites work

1 reference

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Regeneration of adult axons in white matter tracts of the central nervous system

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Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

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Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions

7 April 2017

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Can the immune system be harnessed to repair the CNS?

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Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

28 September 2017

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Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation

28 September 2017

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Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals

28 September 2017

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Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages

28 September 2017

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Toll-like receptors modulate adult hippocampal neurogenesis

28 September 2017

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Characterization and modeling of monocyte-derived macrophages after spinal cord injury

28 September 2017

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Combinatorial treatments for promoting axon regeneration in the CNS: strategies for overcoming inhibitory signals and activating neurons' intrinsic growth state

28 September 2017

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Neuronal regulation by which microglia enhance the production of neurotrophic factors for GABAergic, catecholaminergic, and cholinergic neurons

28 September 2017

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Mammalian toll-like receptors: from endogenous ligands to tissue regeneration.

28 September 2017

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Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

28 September 2017

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HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

28 September 2017

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The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy

28 September 2017

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Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

28 September 2017

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Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system.

28 September 2017

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Macrophages and Microglia Produce Local Trophic Gradients That Stimulate Axonal Sprouting Toward but Not beyond the Wound Edge

28 September 2017

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Innate immunity: the missing link in neuroprotection and neurodegeneration?

28 September 2017

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Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

28 September 2017

1 reference

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An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells

28 September 2017

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The extra domain A of fibronectin activates Toll-like receptor 4.

28 September 2017

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Potential repair of rat spinal cord injuries using stimulated homologous macrophages

28 September 2017

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Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor

28 September 2017

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Brain macrophages: neurotoxic or neurotrophic effector cells?

28 September 2017

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

28 September 2017

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Macrophage-derived factors stimulate optic nerve regeneration.

28 September 2017

1 reference

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Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination

30 May 2018

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Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

30 May 2018

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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

30 May 2018

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Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Macrophage depletion alters the blood-nerve barrier without affecting Schwann cell function after neural injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Systemic injections of lipopolysaccharide accelerates myelin phagocytosis during Wallerian degeneration in the injured mouse spinal cord

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

The effect of stimulated microglia conditioned media on BDNF gene expression of striatal astrocytes: quantification by real-time PCR.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

The contribution of activated phagocytes and myelin degeneration to axonal retraction/dieback following spinal cord injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Hematogenous macrophages express CD8 and distribute to regions of lesion cavitation after spinal cord injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Broad expression of Toll-like receptors in the human central nervous system

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Quantification of neuron survival in monolayer cultures using an enzyme-linked immunosorbent assay approach, rather than by cell counting

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Neurotrophins support the development of diverse sensory axon morphologies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Acute and long-lasting changes in extracellular-matrix chondroitin-sulphate proteoglycans induced by injection of chondroitinase ABC in the adult rat brain

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2693768

Lens injury stimulates axon regeneration in the mature rat optic nerve

28 November 2018

1 reference

12 December 2020

Macrophage recognition of zymosan particles

1 reference

12 December 2020

Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study

1 reference

12 December 2020

Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system

1 reference

12 December 2020

Inflammation near the nerve cell body enhances axonal regeneration

1 reference

12 December 2020

Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

1 reference

12 December 2020

Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord

1 reference

12 December 2020

On the composition of zymosan

1 reference

12 December 2020

Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results

1 reference

12 December 2020

A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia

1 reference

12 December 2020

Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons

1 reference

12 December 2020

A critical role of toll-like receptor 2 in nerve injury-induced spinal cord glial cell activation and pain hypersensitivity

1 reference

12 December 2020

Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury

1 reference

12 December 2020

10.1523/JNEUROSCI.3992-08.2009

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

19321792

1 reference