Can the immune system be harnessed to repair the CNS? (Q37168160)

18 August 2017

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title

Can the immune system be harnessed to repair the CNS? (English)

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18 August 2017

Phillip G Popovich

1

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18 August 2017

Erin E Longbrake

series ordinal

2

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18 August 2017

language of work or name

English

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publication date

1 June 2008

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Nature Reviews Neuroscience

18 August 2017

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18 August 2017

9

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18 August 2017

6

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18 August 2017

481-493

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https://scigraph.springernature.com/pub.10.1038/nrn2398

18 August 2017

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cites work

What is immune privilege (not)?

1 reference

The role of cytokines in the neuropathology of stroke and neurotrauma.

31 March 2020

1 reference

The macrophage in MS: just a scavenger after all? Pathology and pathogenesis of the acute MS lesion

31 March 2020

1 reference

T-cell cytokines in injury-induced neural damage and repair

31 March 2020

1 reference

Harnessing the immune system for neuroprotection: therapeutic vaccines for acute and chronic neurodegenerative disorders

31 March 2020

1 reference

Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries.

31 March 2020

1 reference

Innate (inherent) control of brain infection, brain inflammation and brain repair: the role of microglia, astrocytes, "protective" glial stem cells and stromal ependymal cells

31 March 2020

1 reference

Astrocytes are active players in cerebral innate immunity

31 March 2020

1 reference

Microglia: a sensor for pathological events in the CNS

31 March 2020

1 reference

Points of control in inflammation

31 March 2020

1 reference

The danger model: a renewed sense of self

31 March 2020

1 reference

Friendly and dangerous signals: is the tissue in control?

31 March 2020

1 reference

ATP mediates rapid microglial response to local brain injury in vivo

31 March 2020

1 reference

ATP-mediated glia signaling

31 March 2020

1 reference

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

31 March 2020

1 reference

Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis

31 March 2020

1 reference

Immune function of astrocytes

31 March 2020

1 reference

Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function.

31 March 2020

1 reference

Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha

31 March 2020

1 reference

Microglial control of neuronal death and synaptic properties

31 March 2020

1 reference

Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

31 March 2020

1 reference

Reactive astrocytes protect tissue and preserve function after spinal cord injury

31 March 2020

1 reference

Essential protective roles of reactive astrocytes in traumatic brain injury

31 March 2020

1 reference

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

31 March 2020

1 reference

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

31 March 2020

1 reference

Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury

31 March 2020

1 reference

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

31 March 2020

1 reference

Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

31 March 2020

1 reference

Control of glial immune function by neurons

31 March 2020

1 reference

Innate immunity and protective neuroinflammation: new emphasis on the role of neuroimmune regulatory proteins

31 March 2020

1 reference

Control of microglial neurotoxicity by the fractalkine receptor

31 March 2020

1 reference

Down-regulation of the macrophage lineage through interaction with OX2 (CD200)

31 March 2020

1 reference

Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production.

31 March 2020

1 reference

Reactive astrocytes upregulate Fas (CD95) and Fas ligand (CD95L) expression but do not undergo programmed cell death during the course of anterograde degeneration

31 March 2020

1 reference

Pathobiology of ischaemic stroke: an integrated view

31 March 2020

1 reference

Macrophages are eliminated from the injured peripheral nerve via local apoptosis and circulation to regional lymph nodes and the spleen

31 March 2020

1 reference

Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion.

31 March 2020

1 reference

A blast from the past: clearance of apoptotic cells regulates immune responses.

31 March 2020

1 reference

Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord.

31 March 2020

1 reference

Platelet aggregation in experimental spinal cord injury. Ultrastructural observations

31 March 2020

1 reference

Outcome following decompressive craniectomy for malignant swelling due to severe head injury

31 March 2020

1 reference

Neutral proteases and disruption of the blood-brain barrier in rat

31 March 2020

1 reference

The role of junctional adhesion molecules in vascular inflammation

31 March 2020

1 reference

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

31 March 2020

1 reference

Potentiation of NMDA receptor function by the serine protease thrombin

31 March 2020

1 reference

Participation of protease-activated receptor-1 in thrombin-induced microglial activation

31 March 2020

1 reference

Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.

31 March 2020

1 reference

Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo.

31 March 2020

1 reference

Spinal cord injury triggers systemic autoimmunity: evidence for chronic B lymphocyte activation and lupus-like autoantibody synthesis

31 March 2020

1 reference

Activation of complement pathways after contusion-induced spinal cord injury.

31 March 2020

1 reference

Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation

31 March 2020

1 reference

The role of the complement system in traumatic brain injury

31 March 2020

1 reference

Intrathecal levels of complement-derived soluble membrane attack complex (sC5b-9) correlate with blood-brain barrier dysfunction in patients with traumatic brain injury.

31 March 2020

1 reference

Inflammatory cells during wound repair: the good, the bad and the ugly

31 March 2020

1 reference

Wound healing--aiming for perfect skin regeneration

31 March 2020

1 reference

Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta.

31 March 2020

1 reference

Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

31 March 2020

1 reference

Interleukin-1beta exacerbates and interleukin-1 receptor antagonist attenuates neuronal injury and microglial activation after excitotoxic damage in organotypic hippocampal slice cultures

31 March 2020

1 reference

Regeneration beyond the glial scar

31 March 2020

1 reference

Reactive astrocytes in neural repair and protection

31 March 2020

1 reference

Smad3 null mice display more rapid wound closure and reduced scar formation after a stab wound to the cerebral cortex.

31 March 2020

1 reference

Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes.

31 March 2020

1 reference

Pioneer axon guidance by UNC-129, a C. elegans TGF-beta

31 March 2020

1 reference

Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons.

31 March 2020

1 reference

Suppressors of cytokine signaling and immunity

31 March 2020

1 reference

Cytokine signaling in the brain: putting a SOCS in it?

31 March 2020

1 reference

Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells.

31 March 2020

1 reference

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

31 March 2020

1 reference

Fetal wound healing current perspectives

31 March 2020

1 reference

Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide.

31 March 2020

1 reference

Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation

31 March 2020

1 reference

Efficient central nervous system remyelination requires T cells.

31 March 2020

1 reference

Macrophage-derived factors stimulate optic nerve regeneration.

31 March 2020

1 reference

Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

31 March 2020

1 reference

Activated macrophages and the blood-brain barrier: inflammation after CNS injury leads to increases in putative inhibitory molecules.

31 March 2020

1 reference

The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation.

31 March 2020

1 reference

Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination

31 March 2020

1 reference

T cells contribute to lysophosphatidylcholine-induced macrophage activation and demyelination in the CNS

31 March 2020

1 reference

Liver regeneration: from myth to mechanism

31 March 2020

1 reference

31 March 2020

Inflammation and cancer

1 reference

Systemic injections of lipopolysaccharide accelerates myelin phagocytosis during Wallerian degeneration in the injured mouse spinal cord

31 March 2020

1 reference

Microglia and Macrophage Activation and the Regulation of Complement-Receptor-3 (CR3/MAC-1)-Mediated Myelin Phagocytosis in Injury and Disease

31 March 2020

1 reference

Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages.

31 March 2020

1 reference

Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.

31 March 2020

1 reference

Lens injury stimulates axon regeneration in the mature rat optic nerve

31 March 2020

1 reference

Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve.

31 March 2020

1 reference

Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages.

31 March 2020

1 reference

Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor

31 March 2020

1 reference

Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity

31 March 2020

1 reference

Transplantation of activated macrophages overcomes central nervous system regrowth failure

31 March 2020

1 reference

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

31 March 2020

1 reference

Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1

31 March 2020

1 reference

The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration

31 March 2020

1 reference

Differential effects of central and peripheral nerves on macrophages and microglia.

31 March 2020

1 reference

Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results

31 March 2020

1 reference

Subacute human spinal cord contusion: few lymphocytes and many macrophages

31 March 2020

1 reference

The cellular inflammatory response in human spinal cords after injury.

31 March 2020

1 reference

Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord.

31 March 2020

1 reference

Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

31 March 2020

1 reference

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

31 March 2020

1 reference

Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences

31 March 2020

1 reference

Cytokine-induced acute inflammation in the brain and spinal cord.

31 March 2020

1 reference

Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord

31 March 2020

1 reference

Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis.

31 March 2020

1 reference

Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion.

31 March 2020

1 reference

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

31 March 2020

1 reference

Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNS

31 March 2020

1 reference

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

31 March 2020

1 reference

Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord

31 March 2020

1 reference

Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage

31 March 2020

1 reference

Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

31 March 2020

1 reference

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function.

31 March 2020

1 reference

The promise of minocycline in neurology.

31 March 2020

1 reference

Minocycline treatment in acute stroke: an open-label, evaluator-blinded study.

31 March 2020

1 reference

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

31 March 2020

1 reference

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

31 March 2020

1 reference

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

31 March 2020

1 reference

Therapeutic vaccination for spinal cord injury: helping the body to cure itself.

31 March 2020

1 reference

Pathogenesis of multiple sclerosis.

31 March 2020

1 reference

Augmented locomotor recovery after spinal cord injury in the athymic nude rat

31 March 2020

1 reference

Activated/effector CD4+ T cells exacerbate acute damage in the central nervous system following traumatic injury

31 March 2020

1 reference

Role of T lymphocytes and interferon-gamma in ischemic stroke.

31 March 2020

1 reference

T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats.

31 March 2020

1 reference

Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury.

31 March 2020

1 reference

Immune (dys)regulation in multiple sclerosis: role of the CD95-CD95 ligand system.

31 March 2020

1 reference

The role of TRAIL/TRAIL receptors in central nervous system pathology

31 March 2020

1 reference

Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL.

31 March 2020

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Vulnerability of human neurons to T cell-mediated cytotoxicity

31 March 2020

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Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

31 March 2020

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Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

31 March 2020

1 reference

Semaphorin CD100 from activated T lymphocytes induces process extension collapse in oligodendrocytes and death of immature neural cells

31 March 2020

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Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators.

31 March 2020

1 reference

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

31 March 2020

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Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity

31 March 2020

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Autoreactive T cells induce neurotrophin production by immune and neural cells in injured rat optic nerve: implications for protective autoimmunity

31 March 2020

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Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.

31 March 2020

1 reference

Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury

31 March 2020

1 reference

Immunomodulation by neural stem cells

31 March 2020

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Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli

31 March 2020

1 reference

Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression

31 March 2020

1 reference

Mesenchymal stem cells: a new strategy for immunosuppression?

31 March 2020

1 reference

Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism.

31 March 2020

1 reference

Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cells

31 March 2020

1 reference

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

31 March 2020

1 reference

Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro

31 March 2020

1 reference

Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus

31 March 2020

1 reference

A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord

31 March 2020

1 reference

Amyloid β protein deposition and neuron loss in osteopetrotic (op/op) mice

31 March 2020

1 reference

Recombinant DNA vaccine encoding multiple domains related to inhibition of neurite outgrowth: a potential strategy for axonal regeneration

31 March 2020

1 reference

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

31 March 2020

1 reference

Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet

31 March 2020

1 reference

Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord

31 March 2020

1 reference

Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant.

31 March 2020

1 reference

A T helper cell 2 (Th2) immune response against non-self antigens modifies the cytokine profile of autoimmune T cells and protects against experimental allergic encephalomyelitis

31 March 2020

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The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination

31 March 2020

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Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: comparison with other myelin antigens

31 March 2020

1 reference

Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia

31 March 2020

1 reference

Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells

31 March 2020

1 reference

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

31 March 2020

1 reference

Induction of immunologic tolerance to myelin basic protein prevents central nervous system autoimmunity and improves outcome after stroke

31 March 2020

1 reference

Spinal cord neuropathology in rat experimental autoimmune encephalomyelitis: modulation by oral administration of myelin basic protein

31 March 2020

1 reference

Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis.

31 March 2020

1 reference

Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials

31 March 2020

1 reference

Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial

31 March 2020

1 reference

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

31 March 2020

1 reference

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

31 March 2020

1 reference

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

31 March 2020

1 reference

Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.

31 March 2020

1 reference

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

31 March 2020

1 reference

Abeta species removal after abeta42 immunization.

31 March 2020

1 reference

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

31 March 2020

1 reference

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.

31 March 2020

1 reference

Molecular basis for passive immunotherapy of Alzheimer's disease

31 March 2020

1 reference

Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging.

31 March 2020

1 reference

Glatiramer acetate in multiple sclerosis: update on potential mechanisms of action

31 March 2020

1 reference

T-cell-based vaccination for morphological and functional neuroprotection in a rat model of chronically elevated intraocular pressure.

31 March 2020

1 reference

Randomized controlled phase II trial of glatiramer acetate in ALS

31 March 2020

1 reference

CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

31 March 2020

1 reference

New insights into the mechanism of action of copolymer 1 in experimental allergic encephalomyelitis and multiple sclerosis

31 March 2020

1 reference

T cell independent mechanism for copolymer-1-induced neuroprotection

31 March 2020

1 reference

A novel immune-based therapy for stroke induces neuroprotection and supports neurogenesis

31 March 2020

1 reference

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease

31 March 2020

1 reference

A nasal proteosome adjuvant activates microglia and prevents amyloid deposition

31 March 2020

1 reference

Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes

31 March 2020

1 reference

T-cell design: optimizing the therapeutic potential of autoreactive T cells by genetic modification

31 March 2020

1 reference

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

31 March 2020

1 reference

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

31 March 2020

1 reference

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia.

31 March 2020

1 reference

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

31 March 2020

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Hematopoietic cells maintain hematopoietic fates upon entering the brain.

31 March 2020

1 reference

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

31 March 2020

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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

31 March 2020

1 reference

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice.

31 March 2020

1 reference

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

31 March 2020

1 reference

Migration and differentiation of neural precursor cells can be directed by microglia

31 March 2020

1 reference

Gene therapy: can neural stem cells deliver?

31 March 2020

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Mature astrocytes transform into transitional radial glia within adult mouse neocortex that supports directed migration of transplanted immature neurons

31 March 2020

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Regeneration, tissue injury and the immune response

31 March 2020

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Alternative activation of macrophages

31 March 2020

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Antigen presentation by macrophages is enhanced by the uptake of necrotic, but not apoptotic, cells

31 March 2020

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Excitotoxic and apoptotic neuronal death induce different patterns of glial activation in vitro.

31 March 2020

1 reference

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

31 March 2020

1 reference

The chemokine system in diverse forms of macrophage activation and polarization

31 March 2020

1 reference

Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3.

31 March 2020

1 reference

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

31 March 2020

1 reference

Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity.

31 March 2020

1 reference

Protective autoimmunity is a physiological response to CNS trauma.

31 March 2020

1 reference

Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system

31 March 2020

1 reference

Dual effect of CD4+CD25+ regulatory T cells in neurodegeneration: a dialogue with microglia

31 March 2020

1 reference

Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury

31 March 2020

1 reference

Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease

31 March 2020

1 reference

Multiple sclerosis: a complicated picture of autoimmunity.

31 March 2020

1 reference

Neuroprotection by T-cells depends on their subtype and activation state.

31 March 2020

1 reference

The role of T helper cells in neuroprotection and regeneration

31 March 2020

1 reference

Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease

31 March 2020

1 reference

Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats.

31 March 2020

1 reference

Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS

31 March 2020

1 reference

Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy

31 March 2020

1 reference

Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties.

31 March 2020

1 reference

Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics

31 March 2020

1 reference

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

31 March 2020

1 reference

Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice.

31 March 2020

1 reference

New therapeutic possibility of blocking cytokine-induced neutrophil chemoattractant on transient ischemic brain damage in rats.

31 March 2020

1 reference

Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy

31 March 2020

1 reference

Monoclonal antibody therapy in experimental allergic encephalomyelitis and multiple sclerosis

31 March 2020

1 reference

T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation

31 March 2020

1 reference

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

31 March 2020

1 reference

Therapeutic potential of TACE inhibitors in stroke

31 March 2020

1 reference

UK-279,276, a neutrophil inhibitory glycoprotein, in acute stroke: tolerability and pharmacokinetics

31 March 2020

1 reference

Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke

31 March 2020

1 reference

Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial

31 March 2020

1 reference

A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

31 March 2020

1 reference

Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease

31 March 2020

1 reference

Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of a randomized phase 2 trial.

31 March 2020

1 reference

Abciximab in acute ischemic stroke. A randomized, double-blind, placebo-controlled, dose-escalation study

31 March 2020

1 reference

Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental spinal cord lesion in the rat

31 March 2020

1 reference

Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats.

31 March 2020

1 reference

Methylprednisolone and neurological function 1 year after spinal cord injury. Results of the National Acute Spinal Cord Injury Study

31 March 2020

1 reference

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

31 March 2020

1 reference

Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study

31 March 2020

1 reference

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord I

31 March 2020

1 reference

Methylprednisolone treatment in acute spinal cord injury: the myth challenged through a structured analysis of published literature

31 March 2020

1 reference

Improved recovery after spinal cord trauma in ICAM-1 and P-selectin knockout mice

31 March 2020

1 reference

Role of neutrophils in spinal cord injury in the rat

31 March 2020

1 reference

Role of neutrophil elastase in compression-induced spinal cord injury in rats.

31 March 2020

1 reference

Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration.

31 March 2020

1 reference

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

31 March 2020

1 reference

Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis

31 March 2020

1 reference

Antagonism of the interleukin-1 receptor following traumatic brain injury in the mouse reduces the number of nitric oxide synthase-2-positive cells and improves anatomical and functional outcomes

31 March 2020

1 reference

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

31 March 2020

1 reference

Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.

31 March 2020

1 reference

Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.

31 March 2020

1 reference

IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.

31 March 2020

1 reference

Increased production of tumor necrosis factor-alpha induces apoptosis after traumatic spinal cord injury in rats

31 March 2020

1 reference

Role of tumor necrosis factor-alpha in neuronal and glial apoptosis after spinal cord injury

31 March 2020

1 reference

Features of skin-coincubated macrophages that promote recovery from spinal cord injury

31 March 2020

1 reference

Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion.

31 March 2020

1 reference

Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy.

31 March 2020

1 reference

New directions in MS therapeutics: vehicles of hope

31 March 2020

1 reference

Treatment of multiple sclerosis with mitoxantrone

31 March 2020

1 reference

Randomized placebo-controlled trial of mitoxantrone in relapsing-remitting multiple sclerosis: 24-month clinical and MRI outcome

31 March 2020

1 reference

Mitoxantrone: a review of its use in multiple sclerosis

31 March 2020

1 reference

Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade.

31 March 2020

1 reference

Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis.

31 March 2020

1 reference

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

31 March 2020

1 reference

A controlled trial of natalizumab for relapsing multiple sclerosis.

31 March 2020

1 reference

Randomized multicenter trial of natalizumab in acute MS relapses: clinical and MRI effects

31 March 2020

1 reference

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group

31 March 2020

1 reference

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group

31 March 2020

1 reference

Interferon-beta1a for the treatment of multiple sclerosis

31 March 2020

1 reference

MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination

31 March 2020

1 reference

Glatiramer acetate therapy for multiple sclerosis: a review.

31 March 2020

1 reference

Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis

31 March 2020

1 reference

Progressive multifocal leukoencephalopathy in a patient treated with natalizumab

31 March 2020

1 reference

Biological functions of extravasated serum IgG in rat brain.

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

White matter preservation after spinal cord injury in ICAM-1/P-selectin-deficient mice.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRN2398

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference