Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 (Q24649505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Rodney W. Johnson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Saebyeol Jang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

19 May 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

7534-7539

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

21

1 reference

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describes a project that uses

7 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2396685/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Twenty years of research on cytokine-induced sickness behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Dietary flavonoids: bioavailability, metabolic effects, and safety

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Cancer chemoprevention with dietary phytochemicals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Shifted concentration dependency of EpRE- and XRE-mediated gene expression points at monofunctional EpRE-mediated induction by flavonoids at physiologically relevant concentrations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

JNK signalling: a possible target to prevent neurodegeneration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

The c-jun kinase/stress-activated pathway: regulation, function and role in human disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Systemic infections and inflammation affect chronic neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Aging sensitizes mice to behavioral deficits induced by central HIV-1 gp120

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

JNK pathway as therapeutic target to prevent degeneration in the central nervous system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Bioavailable flavonoids to suppress the formation of 8-OHdG in HepG2 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Neurodegenerative and physiological actions of c-Jun N-terminal kinases in the mammalian brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Flavonoid intake and risk of chronic diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

LPS induction of gene expression in human monocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and proinflammatory cytokine production in macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Induced expression of dominant-negative c-jun downregulates NFkappaB and AP-1 target genes and suppresses tumor phenotype in human keratinocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Intake of flavonoids and risk of dementia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Selective modulation of BV-2 microglial activation by prostaglandin E(2). Differential effects on endotoxin-stimulated cytokine induction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

The flavonoid luteolin prevents lipopolysaccharide-induced NF-kappaB signalling and gene expression by blocking IkappaB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Luteolin inhibits the nuclear factor-kappa B transcriptional activity in Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

c-Jun N-terminal kinases (JNKs) mediate pro-inflammatory actions of microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Regulation of interleukin-6 gene expression in brain of aged mice by nuclear factor kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Comparative study of flavonoids in experimental models of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Susceptibility to immunologically mediated fatigue in C57BL/6 versus Balb/c mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Peripheral infection and aging interact to impair hippocampal memory consolidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Flavonoid permeability across an in situ model of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

alpha-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Alpha-tocopherol attenuates NFkappaB activation and pro-inflammatory cytokine production in brain and improves recovery from lipopolysaccharide-induced sickness behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0802865105

Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kappaB, IRF, and Akt signaling pathways in murine intestinal epithelial cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396685

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18490655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0802865105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

release_sbfz3dxmkjafdobzbi7myuqtae

1 reference

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mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18490655%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2 references