Fission and selective fusion govern mitochondrial segregation and elimination by autophagy (Q24652230)

Gene Ontology release 2020-05-02

1 reference

Gilad Twig

1

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Alvaro Elorza

2

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Anthony J A Molina

3

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Hibo Mohamed

4

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Jakob D Wikstrom

5

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Gil Walzer

6

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Linsey Stiles

7

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Sarah E Haigh

8

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Steve Katz

9

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Guy Las

10

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Joseph Alroy

11

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Min Wu

12

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Bénédicte F Py

13

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Junying Yuan

14

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Jude T Deeney

15

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Barbara E Corkey

16

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Orian S Shirihai

Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence

17

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language of work or name

English

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publication date

23 January 2008

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published in

The EMBO Journal

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volume

27

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issue

2

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page(s)

433-46

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cites work

1 reference

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OPA1 requires mitofusin 1 to promote mitochondrial fusion

7 April 2017

1 reference

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Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology

7 April 2017

1 reference

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The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

7 April 2017

1 reference

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Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

7 April 2017

1 reference

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Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

7 April 2017

1 reference

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Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1

7 April 2017

1 reference

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Mitochondria: dynamic organelles in disease, aging, and development

7 April 2017

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Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death

7 April 2017

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Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

7 April 2017

1 reference

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

7 April 2017

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The role of autophagy during the early neonatal starvation period

7 April 2017

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Autophagy in cell death: an innocent convict?

7 April 2017

1 reference

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

7 April 2017

1 reference

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Mitochondrial dysfunction and type 2 diabetes

7 April 2017

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OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

7 April 2017

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A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

28 September 2017

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Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

28 September 2017

1 reference

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Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

28 September 2017

1 reference

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Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes

28 September 2017

1 reference

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Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells

28 September 2017

1 reference

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Separate fusion of outer and inner mitochondrial membranes.

28 September 2017

1 reference

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Frequent fusion and fission of plant mitochondria with unequal nucleoid distribution.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Mitochondrial membrane potential and aging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Mitochondrial filaments and clusters as intracellular power-transmitting cables

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Mitochondrial fusion intermediates revealed in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Tagging and tracking individual networks within a complex mitochondrial web with photoactivatable GFP.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

The mitochondrial permeability transition initiates autophagy in rat hepatocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234339

Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18200046

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601963

1 reference

455842

455842

1 reference

1 reference

1 reference