WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway (Q24652877)

6

object named as

William B Guggino

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author name string

Bo Zhou

1

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Jieqiu Zhuang

2

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Dingying Gu

3

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Hua Wang

4

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Hui Cai

Journal of the American Society of Nephrology

7

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language of work or name

English

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publication date

January 2010

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published in

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volume

21

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issue

1

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page(s)

82-92

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cites work

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The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin

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Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

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Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

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Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

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Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

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Human hypertension caused by mutations in WNK kinases

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Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

7 April 2017

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Sorting of mannose 6-phosphate receptors mediated by the GGAs

7 April 2017

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Sortilin is a major protein component of Glut4-containing vesicles

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WNK kinases regulate thiazide-sensitive Na-Cl cotransport

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WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

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Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes

7 April 2017

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WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction

7 April 2017

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Mechanism of regulation of renal ion transport by WNK kinases

28 September 2017

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A novel protein kinase signaling pathway essential for blood pressure regulation in humans.

28 September 2017

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Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway.

28 September 2017

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28 September 2017

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ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

28 September 2017

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The trafficking of prosaposin (SGP-1) and GM2AP to the lysosomes of TM4 Sertoli cells is mediated by sortilin and monomeric adaptor proteins

28 September 2017

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28 September 2017

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Coat proteins: shaping membrane transport

28 September 2017

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Characterization of the VPS10 domain of SorLA/LR11 as binding site for the neuropeptide HA.

28 September 2017

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The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein

28 September 2017

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28 September 2017

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Sodium entry mechanisms in distal convoluted tubule cells

28 September 2017

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The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles

28 September 2017

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Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.

30 May 2018

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AP-1 and AP-3 Mediate Sorting of Melanosomal and Lysosomal Membrane Proteins into Distinct Post-Golgi Trafficking Pathways

30 May 2018

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N-Glycosylation at two sites critically alters thiazide binding and activity of the rat thiazide-sensitive Na(+):Cl(-) cotransporter.

28 November 2018

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Identification of fifteen novel mutations in the SLC12A3 gene encoding the Na-Cl Co-transporter in Italian patients with Gitelman syndrome

28 November 2018

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12 December 2020

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