Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane (Q24655380)

1

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Fan Yang

2

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Kathrin Meyer

3

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Catalina Hernandez

4

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Tara Chapman-Arvedson

5

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Caroline A Enns

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

20 June 2008

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published in

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volume

283

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issue

25

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page(s)

17494-502

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cites work

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Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

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A mouse model of juvenile hemochromatosis

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Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

7 April 2017

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Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5

7 April 2017

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

7 April 2017

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The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

7 April 2017

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Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer

7 April 2017

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Complex biosynthesis of the muscle-enriched iron regulator RGMc

7 April 2017

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Regulation of iron metabolism by hepcidin

7 April 2017

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A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

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Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

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7 April 2017

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Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system

7 April 2017

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Isolation and expression pattern of three mouse homologues of chick Rgm

7 April 2017

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

7 April 2017

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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

7 April 2017

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Dynasore, a cell-permeable inhibitor of dynamin

7 April 2017

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7 April 2017

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Balancing acts: molecular control of mammalian iron metabolism

7 April 2017

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Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

7 April 2017

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Cholesterol-sensitive Cdc42 activation regulates actin polymerization for endocytosis via the GEEC pathway

28 September 2017

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Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

28 September 2017

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Neogenin: A multi-functional receptor regulating diverse developmental processes

28 September 2017

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Neogenin: one receptor, many functions

28 September 2017

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28 September 2017

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Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

28 September 2017

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Repulsive guidance molecule/neogenin: a novel ligand-receptor system playing multiple roles in neural development.

28 September 2017

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28 September 2017

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Endosomal dynamics of Met determine signaling output

28 September 2017

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Juvenile hemochromatosis.

28 September 2017

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Natural history of juvenile haemochromatosis

28 September 2017

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Rapid cycling of lipid raft markers between the cell surface and Golgi complex

28 September 2017

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Acute cholesterol depletion inhibits clathrin-coated pit budding

28 September 2017

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Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Synaptic-like microvesicles of neuroendocrine cells originate from a novel compartment that is continuous with the plasma membrane and devoid of transferrin receptor

28 September 2017

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Localization of iron metabolism–related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes

30 May 2018

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Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development.

21 January 2018

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Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin.

21 January 2018

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Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M710527200

Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain.

21 January 2018

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The Netrin receptor Neogenin is required for neural tube formation and somitogenesis in zebrafish

21 January 2018

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Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

21 January 2018

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