The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes (Q24675521)

9

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George Eisenbarth

8

object named as

George S Eisenbarth

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author name string

Janet M Wenzlau

1

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Kirstine Juhl

2

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Liping Yu

3

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Ong Moua

4

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Suparna A Sarkar

5

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Peter Gottlieb

6

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Howard W Davidson

10

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John C Hutton

Proceedings of the National Academy of Sciences of the United States of America

11

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language of work or name

English

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publication date

23 October 2007

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published in

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volume

104

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page(s)

17040-5

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issue

43

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cites work

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

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Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen

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Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient

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A genome-wide association study identifies novel risk loci for type 2 diabetes

7 April 2017

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Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in Type I diabetes

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One third of HLA DQ2 homozygous patients with type 1 diabetes express celiac disease-associated transglutaminase autoantibodies

7 April 2017

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Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein

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Update on major trials for the prevention of type 1 diabetes mellitus: the American Diabetes Prevention Trial (DPT-1) and the European Nicotinamide Diabetes Intervention Trial (ENDIT).

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Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

28 September 2017

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Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes

28 September 2017

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28 September 2017

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

28 September 2017

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Endocrine and immunogenetic testing in individuals with type 1 diabetes and 21-hydroxylase autoantibodies: Addison's disease in a high-risk population

28 September 2017

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Genetic screening for individuals at high risk for type 1 diabetes in the general population using HLA Class II alleles as disease markers. A comparison between three European populations with variable rates of disease incidence

28 November 2018

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Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

28 November 2018

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Survey of mRNAs encoding zinc transporters and other metal complexing proteins in pancreatic islets of rats from birth to adulthood: similar patterns in the Sprague-Dawley and Wistar BB strains.

28 November 2018

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Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.

28 November 2018

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Beta-cell autoantibodies in infants and toddlers without IDDM relatives: diabetes autoimmunity study in the young (DAISY)

28 November 2018

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12 December 2020

Combined analysis of GAD65 and ICA512(IA-2) autoantibodies in organ and non-organ-specific autoimmune diseases confers high specificity for insulin-dependent diabetes mellitus

1 reference

12 December 2020

Development of type 1 diabetes despite severe hereditary B-cell deficiency

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12 December 2020

Type 1 diabetes alters anti-hsp90 autoantibody isotype

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12 December 2020

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

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12 December 2020

Autoantibodies to islet amyloid polypeptide in diabetes

1 reference

12 December 2020

Heterogeneity of islet cell cytoplasmic antibodies and autoantibodies to glutamate decarboxylase in relatives of patients with type 1 (insulin-dependent) diabetes

1 reference

12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

1 reference

12 December 2020

Autoantibodies against GAD65 rather than GAD67 precede the onset of type 1 diabetes

1 reference

12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

1 reference

12 December 2020

Type 1 diabetes risk assessment: improvement by follow-up measurements in young islet autoantibody-positive relatives

1 reference

12 December 2020

RegII is a beta-cell protein and autoantigen in diabetes of NOD mice

1 reference

12 December 2020

Prevalence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity

1 reference

12 December 2020

Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0705894104

1 reference

457433

ADS bibcode

2007PNAS..10417040W

0 references

457433

1 reference

1 reference

1 reference