N-terminus of hMLH1 confers interaction of hMutLalpha and hMutLbeta with hMutSalpha (Q24679608)

5

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author name string

Guido Plotz

1

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Jochen Raedle

2

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Angela Brieger

3

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Jörg Trojan

hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.

4

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language of work or name

English

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publication date

15 June 2003

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published in

Nucleic Acids Research

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volume

31

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issue

12

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page(s)

3217-26

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cites work

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Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha

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MutS mediates heteroduplex loop formation by a translocation mechanism

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The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions

28 September 2017

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28 September 2017

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28 September 2017

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Replication errors: cha(lle)nging the genome

28 September 2017

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Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

30 May 2018

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30 May 2018

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28 November 2018

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DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes

28 November 2018

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Mutation in the magnesium binding site of hMSH6 disables the hMutSalpha sliding clamp from translocating along DNA

28 November 2018

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Mismatch repair, molecular switches, and signal transduction

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Alternative splicing of MLH1 messenger RNA in human normal cells.

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Modulation of MutS ATP hydrolysis by DNA cofactors

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12 December 2020

The MutL ATPase is required for mismatch repair

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12 December 2020

Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells

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12 December 2020

Interaction of Escherichia coli MutS and MutL at a DNA mismatch

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12 December 2020

Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer

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12 December 2020

The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity

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12 December 2020

The role of hPMS1 and hPMS2 in predisposing to colorectal cancer

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12 December 2020

Repair of DNA base-pair mismatches in extracts of Escherichia coli

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12 December 2020

Initiation of methyl-directed mismatch repair

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12 December 2020

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

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12 December 2020